Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019
H10, H11 and H12 (H10–H12) subtypes of the avian influenza virus (AIV) are associated with waterfowl. Although these subtypes of AIV are infrequently detected in nature, they can undergo reassortment with other AIV subtypes. Few H10–H12 subtypes of AIV have been isolated from wild birds in China. In...
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MDPI AG
2020-09-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/12/10/1085 |
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| author | Ling Tang Wangjun Tang Le Ming Jianming Gu Kai Qian Xiaofang Li Tianhou Wang Guimei He |
| author_facet | Ling Tang Wangjun Tang Le Ming Jianming Gu Kai Qian Xiaofang Li Tianhou Wang Guimei He |
| author_sort | Ling Tang |
| collection | DOAJ |
| description | H10, H11 and H12 (H10–H12) subtypes of the avian influenza virus (AIV) are associated with waterfowl. Although these subtypes of AIV are infrequently detected in nature, they can undergo reassortment with other AIV subtypes. Few H10–H12 subtypes of AIV have been isolated from wild birds in China. In this study, 12 AIV isolates of H10–H12 subtypes were identified via routine surveillance of wild birds in Shanghai, China from 2016 to 2019, including two H10, three H11 and seven H12 isolates. Sequence and phylogenetic analyses revealed that the genomic segments of the 12 isolates are highly diverse. These 12 isolates are closely related to those in the Eurasian lineage and share a high degree of sequence identity with those from wild birds and domestic ducks in countries in the East Asian–Australasian Flyway, including Japan, Korea, Bangladesh, Vietnam and China. However, parts of the genomic segments of two H12N2 isolates (NH112319-H12N2 and NH101807-H12N2) belong to the North American lineage, suggesting intercontinental reassortment among H12 AIVs in Eurasia and North American. To better understand the ecological and phylodynamic features of H10–H12 subtypes in wild birds, a large-scale surveillance of AIVs in wild birds is warranted. |
| first_indexed | 2024-03-10T16:02:27Z |
| format | Article |
| id | doaj.art-24b12c7677404e51a5c2969c2661bd4b |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T16:02:27Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-24b12c7677404e51a5c2969c2661bd4b2023-11-20T15:09:41ZengMDPI AGViruses1999-49152020-09-011210108510.3390/v12101085Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019Ling Tang0Wangjun Tang1Le Ming2Jianming Gu3Kai Qian4Xiaofang Li5Tianhou Wang6Guimei He7Laboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaLaboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaLaboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaPudong District Forestry Station of Shanghai, Shanghai 200120, ChinaPudong District Forestry Station of Shanghai, Shanghai 200120, ChinaLaboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaLaboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaLaboratory of Wildlife Epidemic Diseases, School of Life Sciences, East China Normal University, Shanghai 200063, ChinaH10, H11 and H12 (H10–H12) subtypes of the avian influenza virus (AIV) are associated with waterfowl. Although these subtypes of AIV are infrequently detected in nature, they can undergo reassortment with other AIV subtypes. Few H10–H12 subtypes of AIV have been isolated from wild birds in China. In this study, 12 AIV isolates of H10–H12 subtypes were identified via routine surveillance of wild birds in Shanghai, China from 2016 to 2019, including two H10, three H11 and seven H12 isolates. Sequence and phylogenetic analyses revealed that the genomic segments of the 12 isolates are highly diverse. These 12 isolates are closely related to those in the Eurasian lineage and share a high degree of sequence identity with those from wild birds and domestic ducks in countries in the East Asian–Australasian Flyway, including Japan, Korea, Bangladesh, Vietnam and China. However, parts of the genomic segments of two H12N2 isolates (NH112319-H12N2 and NH101807-H12N2) belong to the North American lineage, suggesting intercontinental reassortment among H12 AIVs in Eurasia and North American. To better understand the ecological and phylodynamic features of H10–H12 subtypes in wild birds, a large-scale surveillance of AIVs in wild birds is warranted.https://www.mdpi.com/1999-4915/12/10/1085avian influenza virusH10–H12 subtypesphylogenetic analysissurveillancewild birds |
| spellingShingle | Ling Tang Wangjun Tang Le Ming Jianming Gu Kai Qian Xiaofang Li Tianhou Wang Guimei He Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 Viruses avian influenza virus H10–H12 subtypes phylogenetic analysis surveillance wild birds |
| title | Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 |
| title_full | Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 |
| title_fullStr | Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 |
| title_full_unstemmed | Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 |
| title_short | Characterization of Avian Influenza Virus H10–H12 Subtypes Isolated from Wild Birds in Shanghai, China from 2016 to 2019 |
| title_sort | characterization of avian influenza virus h10 h12 subtypes isolated from wild birds in shanghai china from 2016 to 2019 |
| topic | avian influenza virus H10–H12 subtypes phylogenetic analysis surveillance wild birds |
| url | https://www.mdpi.com/1999-4915/12/10/1085 |
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