National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment

In June 2014, the national experts on diabetes mellitus discussed the opportunities to improve the efficacy and outcomes of diabetes treatment using the strategy of patient-oriented care in diabetes. Insulin degludec (Tresiba?) is a new basal ultra-long-acting insulin analogue with a flat, stable gl...

Full description

Bibliographic Details
Main Author: Gagik Radikovich Galstyan
Format: Article
Language:English
Published: Endocrinology Research Centre 2014-10-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/6698
_version_ 1826588093938925568
author Gagik Radikovich Galstyan
author_facet Gagik Radikovich Galstyan
author_sort Gagik Radikovich Galstyan
collection DOAJ
description In June 2014, the national experts on diabetes mellitus discussed the opportunities to improve the efficacy and outcomes of diabetes treatment using the strategy of patient-oriented care in diabetes. Insulin degludec (Tresiba?) is a new basal ultra-long-acting insulin analogue with a flat, stable glucose-lowering profile, ultra-long duration of action (>=42 h) and less within-patient day-to-day variability in glucose-lowering effect compared with currently available basal insulins. In the clinical trial programme, insulin degludec showed a similar glycaemic control compared with insulin glargine using the same insulin dose, but with a lower risk of hypoglycaemia and a greater flexibility in the time of dosing on a daily basis, when needed. Thus, the use of insulin degludec in routine clinical practice provides an effective and improved treatment for type 1 and 2 diabetes. The simple algorithm titration of insulin degludec offers the opportunity to personalise treatment regimens according to the needs of each patient.
first_indexed 2024-03-08T15:21:01Z
format Article
id doaj.art-24b4ef9c9f704b85892f4bf526c0a719
institution Directory Open Access Journal
issn 2072-0351
2072-0378
language English
last_indexed 2025-03-14T16:35:51Z
publishDate 2014-10-01
publisher Endocrinology Research Centre
record_format Article
series Сахарный диабет
spelling doaj.art-24b4ef9c9f704b85892f4bf526c0a7192025-02-21T09:29:32ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782014-10-0117312913310.14341/DM20143129-1336502National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatmentGagik Radikovich Galstyan0Endocrinology Research Centre, Moscow; Sechenov First Moscow State Medical University, MoscowIn June 2014, the national experts on diabetes mellitus discussed the opportunities to improve the efficacy and outcomes of diabetes treatment using the strategy of patient-oriented care in diabetes. Insulin degludec (Tresiba?) is a new basal ultra-long-acting insulin analogue with a flat, stable glucose-lowering profile, ultra-long duration of action (>=42 h) and less within-patient day-to-day variability in glucose-lowering effect compared with currently available basal insulins. In the clinical trial programme, insulin degludec showed a similar glycaemic control compared with insulin glargine using the same insulin dose, but with a lower risk of hypoglycaemia and a greater flexibility in the time of dosing on a daily basis, when needed. Thus, the use of insulin degludec in routine clinical practice provides an effective and improved treatment for type 1 and 2 diabetes. The simple algorithm titration of insulin degludec offers the opportunity to personalise treatment regimens according to the needs of each patient.https://www.dia-endojournals.ru/jour/article/view/6698diabetes mellitusglycaemic controlbasal insulindegludechypoglycaemiacardiovascular safety
spellingShingle Gagik Radikovich Galstyan
National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
Сахарный диабет
diabetes mellitus
glycaemic control
basal insulin
degludec
hypoglycaemia
cardiovascular safety
title National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
title_full National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
title_fullStr National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
title_full_unstemmed National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
title_short National advisory board on diabetes mellitus: unsolved issues and new opportunities for diabetes treatment
title_sort national advisory board on diabetes mellitus unsolved issues and new opportunities for diabetes treatment
topic diabetes mellitus
glycaemic control
basal insulin
degludec
hypoglycaemia
cardiovascular safety
url https://www.dia-endojournals.ru/jour/article/view/6698
work_keys_str_mv AT gagikradikovichgalstyan nationaladvisoryboardondiabetesmellitusunsolvedissuesandnewopportunitiesfordiabetestreatment