Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment.

Single-cell analysis of a high-grade serous ovarian cancer cell line reveals transcriptomic changes and cell subpopulations sensitive to epigenetic combination treatment.

अन्य संस्करण दिखाएं (1)

Ovarian cancer (OC) is a lethal gynecological malignancy with a five-year survival rate of only 46%. Development of resistance to platinum-based chemotherapy is a common cause of high mortality rates among OC patients. Tumor and transcriptomic heterogeneity are drivers of platinum resistance in OC....

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Shruthi Sriramkumar, Tara X Metcalfe, Tim Lai, Xingyue Zong, Fang Fang, Heather M O'Hagan, Kenneth P Nephew
स्वरूप:	लेख
भाषा:	English
प्रकाशित:	Public Library of Science (PLoS) 2022-01-01
श्रृंखला:	PLoS ONE
ऑनलाइन पहुंच:	https://doi.org/10.1371/journal.pone.0271584

समान संसाधन

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