Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias

The authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can b...

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Main Authors: Yu. N. Ponomareva, I. B. Manukhin, L. A. Ashrafyan
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/221
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author Yu. N. Ponomareva
I. B. Manukhin
L. A. Ashrafyan
author_facet Yu. N. Ponomareva
I. B. Manukhin
L. A. Ashrafyan
author_sort Yu. N. Ponomareva
collection DOAJ
description The authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can be effectively used in the diagnosis and prediction of cervical neoplasias to optimize management tac- tics and to improve the results of treatment.
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spelling doaj.art-24b93f9e579641f6b0c3f4a67f501d552025-03-02T13:05:30ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0101727510.17650/1994-4098-2010-0-1-72-75237Molecular biological factors in the diagnosis of cervical intraepithelial neoplasiasYu. N. Ponomareva0I. B. Manukhin1L. A. Ashrafyan2Moscow Regional Hospital FiveDepartment of Obstetrics and Gynecology, Moscow State University of Medicine and DentistryRussian X-ray Radiology Research Center, Russian Agency for Medical Technologies, MoscowThe authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can be effectively used in the diagnosis and prediction of cervical neoplasias to optimize management tac- tics and to improve the results of treatment.https://ojrs.abvpress.ru/ojrs/article/view/221cervix utericervical neoplasiaapoptosisproliferation
spellingShingle Yu. N. Ponomareva
I. B. Manukhin
L. A. Ashrafyan
Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
Опухоли женской репродуктивной системы
cervix uteri
cervical neoplasia
apoptosis
proliferation
title Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
title_full Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
title_fullStr Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
title_full_unstemmed Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
title_short Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
title_sort molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
topic cervix uteri
cervical neoplasia
apoptosis
proliferation
url https://ojrs.abvpress.ru/ojrs/article/view/221
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AT ibmanukhin molecularbiologicalfactorsinthediagnosisofcervicalintraepithelialneoplasias
AT laashrafyan molecularbiologicalfactorsinthediagnosisofcervicalintraepithelialneoplasias