Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
The authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can b...
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Format: | Article |
Language: | Russian |
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ABV-press
2014-08-01
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Series: | Опухоли женской репродуктивной системы |
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Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/221 |
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author | Yu. N. Ponomareva I. B. Manukhin L. A. Ashrafyan |
author_facet | Yu. N. Ponomareva I. B. Manukhin L. A. Ashrafyan |
author_sort | Yu. N. Ponomareva |
collection | DOAJ |
description | The authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can be effectively used in the diagnosis and prediction of cervical neoplasias to optimize management tac- tics and to improve the results of treatment. |
first_indexed | 2024-04-10T01:57:17Z |
format | Article |
id | doaj.art-24b93f9e579641f6b0c3f4a67f501d55 |
institution | Directory Open Access Journal |
issn | 1994-4098 1999-8627 |
language | Russian |
last_indexed | 2025-03-14T08:26:45Z |
publishDate | 2014-08-01 |
publisher | ABV-press |
record_format | Article |
series | Опухоли женской репродуктивной системы |
spelling | doaj.art-24b93f9e579641f6b0c3f4a67f501d552025-03-02T13:05:30ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0101727510.17650/1994-4098-2010-0-1-72-75237Molecular biological factors in the diagnosis of cervical intraepithelial neoplasiasYu. N. Ponomareva0I. B. Manukhin1L. A. Ashrafyan2Moscow Regional Hospital FiveDepartment of Obstetrics and Gynecology, Moscow State University of Medicine and DentistryRussian X-ray Radiology Research Center, Russian Agency for Medical Technologies, MoscowThe authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can be effectively used in the diagnosis and prediction of cervical neoplasias to optimize management tac- tics and to improve the results of treatment.https://ojrs.abvpress.ru/ojrs/article/view/221cervix utericervical neoplasiaapoptosisproliferation |
spellingShingle | Yu. N. Ponomareva I. B. Manukhin L. A. Ashrafyan Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias Опухоли женской репродуктивной системы cervix uteri cervical neoplasia apoptosis proliferation |
title | Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
title_full | Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
title_fullStr | Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
title_full_unstemmed | Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
title_short | Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
title_sort | molecular biological factors in the diagnosis of cervical intraepithelial neoplasias |
topic | cervix uteri cervical neoplasia apoptosis proliferation |
url | https://ojrs.abvpress.ru/ojrs/article/view/221 |
work_keys_str_mv | AT yunponomareva molecularbiologicalfactorsinthediagnosisofcervicalintraepithelialneoplasias AT ibmanukhin molecularbiologicalfactorsinthediagnosisofcervicalintraepithelialneoplasias AT laashrafyan molecularbiologicalfactorsinthediagnosisofcervicalintraepithelialneoplasias |