Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients
The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2018-10-01
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| Series: | Clinical and Experimental Hypertension |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641963.2017.1416119 |
| _version_ | 1827814311588790272 |
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| author | Minako Inoue Kiyoshi Matsumura Yoshie Haga Yasuo Kansui Kenichi Goto Toshio Ohtsubo Takanari Kitazono |
| author_facet | Minako Inoue Kiyoshi Matsumura Yoshie Haga Yasuo Kansui Kenichi Goto Toshio Ohtsubo Takanari Kitazono |
| author_sort | Minako Inoue |
| collection | DOAJ |
| description | The relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension. |
| first_indexed | 2024-03-11T23:43:44Z |
| format | Article |
| id | doaj.art-24be68bbe3e241f593fc66f7f703e227 |
| institution | Directory Open Access Journal |
| issn | 1064-1963 1525-6006 |
| language | English |
| last_indexed | 2024-03-11T23:43:44Z |
| publishDate | 2018-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Clinical and Experimental Hypertension |
| spelling | doaj.art-24be68bbe3e241f593fc66f7f703e2272023-09-19T15:19:26ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062018-10-0140762463010.1080/10641963.2017.14161191416119Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patientsMinako Inoue0Kiyoshi Matsumura1Yoshie Haga2Yasuo Kansui3Kenichi Goto4Toshio Ohtsubo5Takanari Kitazono6Graduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityGraduate School of Medical Sciences, Kyushu UniversityThe relationship between the renin–angiotensin aldosterone system and short-term blood pressure variability has not been well elucidated. Here, we investigated whether blood pressure variability determined by ambulatory blood pressure monitoring differed among patients with primary aldosteronism (PA), renovascular hypertension (RVHT), and essential hypertension (EHT). We examined 25 patients with PA, 28 patients with RVHT, and 18 patients with EHT. Ambulatory blood pressure monitoring was conducted in all patients. Short-term blood pressure variability was evaluated by calculating the standard deviation (SD), coefficient of variation (CV), and average real variability (ARV) of 24-h, daytime, and nighttime blood pressure values. Day–night differences in blood pressure were also determined. The mean 24-h systolic blood pressure (SBP) and the mean diastolic blood pressure (DBP) in the PA and RVHT groups were found to be comparable to those in the EHT group. The SD, the CV, nor the ARV of the 24-h, daytime, and nighttime blood pressures showed any significant differences among the three groups. The day–night differences in blood pressure were comparable among the three groups. The short-term blood pressure variabilities evaluated by ambulatory blood pressure monitoring were comparable among the patients with EHT, RVHT, and PA. The results suggest that the renin–angiotensin aldosterone system may contribute little to short-term blood pressure variability in individuals with hypertension.http://dx.doi.org/10.1080/10641963.2017.1416119hypertensionrenin-angiotensin aldosterone systemshort-term blood pressure variability |
| spellingShingle | Minako Inoue Kiyoshi Matsumura Yoshie Haga Yasuo Kansui Kenichi Goto Toshio Ohtsubo Takanari Kitazono Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients Clinical and Experimental Hypertension hypertension renin-angiotensin aldosterone system short-term blood pressure variability |
| title | Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients |
| title_full | Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients |
| title_fullStr | Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients |
| title_full_unstemmed | Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients |
| title_short | Role of renin–angiotensin aldosterone system on short-term blood pressure variability in hypertensive patients |
| title_sort | role of renin angiotensin aldosterone system on short term blood pressure variability in hypertensive patients |
| topic | hypertension renin-angiotensin aldosterone system short-term blood pressure variability |
| url | http://dx.doi.org/10.1080/10641963.2017.1416119 |
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