Plant Biosystems Design Research Roadmap 1.0
Human life intimately depends on plants for food, biomaterials, health, energy, and a sustainable environment. Various plants have been genetically improved mostly through breeding, along with limited modification via genetic engineering, yet they are still not able to meet the ever-increasing needs...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science (AAAS)
2020-01-01
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| Series: | BioDesign Research |
| Online Access: | http://dx.doi.org/10.34133/2020/8051764 |
| _version_ | 1797283643308113920 |
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| author | Xiaohan Yang June I. Medford Kasey Markel Patrick M. Shih Henrique C. De Paoli Cong T. Trinh Alistair J. McCormick Raphael Ployet Steven G. Hussey Alexander A. Myburg Poul Erik Jensen Md Mahmudul Hassan Jin Zhang Wellington Muchero Udaya C. Kalluri Hengfu Yin Renying Zhuo Paul E. Abraham Jin-Gui Chen David J. Weston Yinong Yang Degao Liu Yi Li Jessy Labbe Bing Yang Jun Hyung Lee Robert W. Cottingham Stanton Martin Mengzhu Lu Timothy J. Tschaplinski Guoliang Yuan Haiwei Lu Priya Ranjan Julie C. Mitchell Stan D. Wullschleger Gerald A. Tuskan |
| author_facet | Xiaohan Yang June I. Medford Kasey Markel Patrick M. Shih Henrique C. De Paoli Cong T. Trinh Alistair J. McCormick Raphael Ployet Steven G. Hussey Alexander A. Myburg Poul Erik Jensen Md Mahmudul Hassan Jin Zhang Wellington Muchero Udaya C. Kalluri Hengfu Yin Renying Zhuo Paul E. Abraham Jin-Gui Chen David J. Weston Yinong Yang Degao Liu Yi Li Jessy Labbe Bing Yang Jun Hyung Lee Robert W. Cottingham Stanton Martin Mengzhu Lu Timothy J. Tschaplinski Guoliang Yuan Haiwei Lu Priya Ranjan Julie C. Mitchell Stan D. Wullschleger Gerald A. Tuskan |
| author_sort | Xiaohan Yang |
| collection | DOAJ |
| description | Human life intimately depends on plants for food, biomaterials, health, energy, and a sustainable environment. Various plants have been genetically improved mostly through breeding, along with limited modification via genetic engineering, yet they are still not able to meet the ever-increasing needs, in terms of both quantity and quality, resulting from the rapid increase in world population and expected standards of living. A step change that may address these challenges would be to expand the potential of plants using biosystems design approaches. This represents a shift in plant science research from relatively simple trial-and-error approaches to innovative strategies based on predictive models of biological systems. Plant biosystems design seeks to accelerate plant genetic improvement using genome editing and genetic circuit engineering or create novel plant systems through de novo synthesis of plant genomes. From this perspective, we present a comprehensive roadmap of plant biosystems design covering theories, principles, and technical methods, along with potential applications in basic and applied plant biology research. We highlight current challenges, future opportunities, and research priorities, along with a framework for international collaboration, towards rapid advancement of this emerging interdisciplinary area of research. Finally, we discuss the importance of social responsibility in utilizing plant biosystems design and suggest strategies for improving public perception, trust, and acceptance. |
| first_indexed | 2024-03-07T17:34:47Z |
| format | Article |
| id | doaj.art-24bf47722b144d758d6e3c016167a800 |
| institution | Directory Open Access Journal |
| issn | 2693-1257 |
| language | English |
| last_indexed | 2024-03-07T17:34:47Z |
| publishDate | 2020-01-01 |
| publisher | American Association for the Advancement of Science (AAAS) |
| record_format | Article |
| series | BioDesign Research |
| spelling | doaj.art-24bf47722b144d758d6e3c016167a8002024-03-02T17:07:38ZengAmerican Association for the Advancement of Science (AAAS)BioDesign Research2693-12572020-01-01202010.34133/2020/8051764Plant Biosystems Design Research Roadmap 1.0Xiaohan Yang0June I. Medford1Kasey Markel2Patrick M. Shih3Henrique C. De Paoli4Cong T. Trinh5Alistair J. McCormick6Raphael Ployet7Steven G. Hussey8Alexander A. Myburg9Poul Erik Jensen10Md Mahmudul Hassan11Jin Zhang12Wellington Muchero13Udaya C. Kalluri14Hengfu Yin15Renying Zhuo16Paul E. Abraham17Jin-Gui Chen18David J. Weston19Yinong Yang20Degao Liu21Yi Li22Jessy Labbe23Bing Yang24Jun Hyung Lee25Robert W. Cottingham26Stanton Martin27Mengzhu Lu28Timothy J. Tschaplinski29Guoliang Yuan30Haiwei Lu31Priya Ranjan32Julie C. Mitchell33Stan D. Wullschleger34Gerald A. Tuskan35Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USADepartment of Biology, Colorado State University, Fort Collins, CO 80523, USADepartment of Plant Biology, University of California, Davis, Davis, CA, USADepartment of Plant Biology, University of California, Davis, Davis, CA, USA; Feedstocks Division, Joint BioEnergy Institute, Emeryville, CA, USADepartment of Biodesign, Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USAThe Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN 37996, USASynthSys and Institute of Molecular Plant Sciences, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UKDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria 0002, South AfricaDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria 0002, South AfricaDepartment of Biochemistry, Genetics and Microbiology, Forestry and Agricultural Biotechnology Institute (FABI), University of Pretoria, Pretoria 0002, South AfricaDepartment of Food Science, University of Copenhagen, Rolighedsvej 26, DK-1858, Frederiksberg, Copenhagen, DenmarkBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; State Key Laboratory of Subtropical Silviculture, School of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou, Zhejiang 311300, ChinaBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USAState Key Laboratory of Tree Genetics and Breeding, Research Institute of Subtropical Forestry, Chinese Academy of Forestry, Hangzhou, Zhejiang 311400, ChinaState Key Laboratory of Tree Genetics and Breeding, Research Institute of Subtropical Forestry, Chinese Academy of Forestry, Hangzhou, Zhejiang 311400, ChinaBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USADepartment of Plant Pathology and Environmental Microbiology and the Huck Institute of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USADepartment of Genetics, Cell Biology and Development, Center for Precision Plant Genomics and Center for Genome Engineering, University of Minnesota, Saint Paul, MN 55108, USADepartment of Plant Science and Landscape Architecture, University of Connecticut, Storrs, CT 06269, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USADivision of Plant Sciences, Bond Life Sciences Center, University of Missouri, Columbia, MO, USA; Donald Danforth Plant Science Center, St. Louis, MO, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USAState Key Laboratory of Subtropical Silviculture, School of Forestry and Biotechnology, Zhejiang A&F University, Hangzhou, Zhejiang 311300, ChinaBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USAEnvironmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USABiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA; The Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USAHuman life intimately depends on plants for food, biomaterials, health, energy, and a sustainable environment. Various plants have been genetically improved mostly through breeding, along with limited modification via genetic engineering, yet they are still not able to meet the ever-increasing needs, in terms of both quantity and quality, resulting from the rapid increase in world population and expected standards of living. A step change that may address these challenges would be to expand the potential of plants using biosystems design approaches. This represents a shift in plant science research from relatively simple trial-and-error approaches to innovative strategies based on predictive models of biological systems. Plant biosystems design seeks to accelerate plant genetic improvement using genome editing and genetic circuit engineering or create novel plant systems through de novo synthesis of plant genomes. From this perspective, we present a comprehensive roadmap of plant biosystems design covering theories, principles, and technical methods, along with potential applications in basic and applied plant biology research. We highlight current challenges, future opportunities, and research priorities, along with a framework for international collaboration, towards rapid advancement of this emerging interdisciplinary area of research. Finally, we discuss the importance of social responsibility in utilizing plant biosystems design and suggest strategies for improving public perception, trust, and acceptance.http://dx.doi.org/10.34133/2020/8051764 |
| spellingShingle | Xiaohan Yang June I. Medford Kasey Markel Patrick M. Shih Henrique C. De Paoli Cong T. Trinh Alistair J. McCormick Raphael Ployet Steven G. Hussey Alexander A. Myburg Poul Erik Jensen Md Mahmudul Hassan Jin Zhang Wellington Muchero Udaya C. Kalluri Hengfu Yin Renying Zhuo Paul E. Abraham Jin-Gui Chen David J. Weston Yinong Yang Degao Liu Yi Li Jessy Labbe Bing Yang Jun Hyung Lee Robert W. Cottingham Stanton Martin Mengzhu Lu Timothy J. Tschaplinski Guoliang Yuan Haiwei Lu Priya Ranjan Julie C. Mitchell Stan D. Wullschleger Gerald A. Tuskan Plant Biosystems Design Research Roadmap 1.0 BioDesign Research |
| title | Plant Biosystems Design Research Roadmap 1.0 |
| title_full | Plant Biosystems Design Research Roadmap 1.0 |
| title_fullStr | Plant Biosystems Design Research Roadmap 1.0 |
| title_full_unstemmed | Plant Biosystems Design Research Roadmap 1.0 |
| title_short | Plant Biosystems Design Research Roadmap 1.0 |
| title_sort | plant biosystems design research roadmap 1 0 |
| url | http://dx.doi.org/10.34133/2020/8051764 |
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