Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction
Objective: to determine the impact of early initiation of renal replacement therapy on the manifestations of a systemic inflammatory response (SIR) and on the prevention of progression of organ dysfunction (OD). Subjects and methods. A prospective study was conducted in the intensive care units of t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2010-12-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/362 |
| _version_ | 1797874320148529152 |
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| author | L. S. Barbarash G. P. Plotnikov D. L. Shukevich B. L. Hayes L. E. Shukevich Yu. A. Churlyav Ye. V. Grigoryev |
| author_facet | L. S. Barbarash G. P. Plotnikov D. L. Shukevich B. L. Hayes L. E. Shukevich Yu. A. Churlyav Ye. V. Grigoryev |
| author_sort | L. S. Barbarash |
| collection | DOAJ |
| description | Objective: to determine the impact of early initiation of renal replacement therapy on the manifestations of a systemic inflammatory response (SIR) and on the prevention of progression of organ dysfunction (OD). Subjects and methods. A prospective study was conducted in the intensive care units of the Kemerovo Regional Clinical Hospital and the Research Institute for Integrated Problems of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences, in the identical period (2003—2009). Three hundred and fifty-four patients underwent a set of invasive hemodynamic studies, biochemical tests, and transpulmonary thermodilution. Conclusion. Renal replacement therapy prevents the progression of OD in patients with SIR irrespective of the etiology of the latter (infectious versus noninfectious SIR); the earlier initiation of continuous renal replacement therapy (within 24 hours after the determination of indications for its session) is most effective. Key words: renal replacement therapy, organ dysfunction. |
| first_indexed | 2024-04-10T01:29:03Z |
| format | Article |
| id | doaj.art-24c52adcfaaf418c92870caab9891ace |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2024-04-10T01:29:03Z |
| publishDate | 2010-12-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-24c52adcfaaf418c92870caab9891ace2023-03-13T09:32:50ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102010-12-016610.15360/1813-9779-2010-6-29362Rationale for Early Renal Replacement Therapy for Multiple Organ DysfunctionL. S. BarbarashG. P. PlotnikovD. L. ShukevichB. L. HayesL. E. ShukevichYu. A. ChurlyavYe. V. GrigoryevObjective: to determine the impact of early initiation of renal replacement therapy on the manifestations of a systemic inflammatory response (SIR) and on the prevention of progression of organ dysfunction (OD). Subjects and methods. A prospective study was conducted in the intensive care units of the Kemerovo Regional Clinical Hospital and the Research Institute for Integrated Problems of Cardiovascular Diseases, Siberian Branch of the Russian Academy of Medical Sciences, in the identical period (2003—2009). Three hundred and fifty-four patients underwent a set of invasive hemodynamic studies, biochemical tests, and transpulmonary thermodilution. Conclusion. Renal replacement therapy prevents the progression of OD in patients with SIR irrespective of the etiology of the latter (infectious versus noninfectious SIR); the earlier initiation of continuous renal replacement therapy (within 24 hours after the determination of indications for its session) is most effective. Key words: renal replacement therapy, organ dysfunction.https://www.reanimatology.com/rmt/article/view/362 |
| spellingShingle | L. S. Barbarash G. P. Plotnikov D. L. Shukevich B. L. Hayes L. E. Shukevich Yu. A. Churlyav Ye. V. Grigoryev Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction Общая реаниматология |
| title | Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction |
| title_full | Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction |
| title_fullStr | Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction |
| title_full_unstemmed | Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction |
| title_short | Rationale for Early Renal Replacement Therapy for Multiple Organ Dysfunction |
| title_sort | rationale for early renal replacement therapy for multiple organ dysfunction |
| url | https://www.reanimatology.com/rmt/article/view/362 |
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