Human Papillomavirus Vaccines: An Updated Review
Human papillomavirus (HPV) vaccines, which were introduced in many countries in the past decade, have shown promising results in decreasing HPV infection and related diseases, such as warts and precancerous lesions. In this review, we present the updated information about current HPV vaccines, focus...
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Format: | Article |
Language: | English |
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MDPI AG
2020-07-01
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Series: | Vaccines |
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Online Access: | https://www.mdpi.com/2076-393X/8/3/391 |
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author | Liqin Cheng Yan Wang Juan Du |
author_facet | Liqin Cheng Yan Wang Juan Du |
author_sort | Liqin Cheng |
collection | DOAJ |
description | Human papillomavirus (HPV) vaccines, which were introduced in many countries in the past decade, have shown promising results in decreasing HPV infection and related diseases, such as warts and precancerous lesions. In this review, we present the updated information about current HPV vaccines, focusing on vaccine coverage and efficacy. In addition, pan-gender vaccination and current clinical trials are also discussed. Currently, more efforts should be put into increasing the vaccine’s coverage, especially in low- and middle-income countries. Provision of education on HPV and vaccination is one of the most important methods to achieve this. Vaccines that target HPV types not included in current vaccines are the next stage in vaccine development. In the future, all HPV-related cancers, such as head and neck cancer, and anal cancer, should be tracked and evaluated, especially in countries that have introduced pan-gender vaccination programs. Therapeutic vaccines, in combination with other cancer treatments, should continue to be investigated. |
first_indexed | 2024-03-10T18:26:25Z |
format | Article |
id | doaj.art-24c7a73a5051409992f520c437963a99 |
institution | Directory Open Access Journal |
issn | 2076-393X |
language | English |
last_indexed | 2024-03-10T18:26:25Z |
publishDate | 2020-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Vaccines |
spelling | doaj.art-24c7a73a5051409992f520c437963a992023-11-20T06:59:35ZengMDPI AGVaccines2076-393X2020-07-018339110.3390/vaccines8030391Human Papillomavirus Vaccines: An Updated ReviewLiqin Cheng0Yan Wang1Juan Du2Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 17177 Stockholm, SwedenDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 17177 Stockholm, SwedenDepartment of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, 17177 Stockholm, SwedenHuman papillomavirus (HPV) vaccines, which were introduced in many countries in the past decade, have shown promising results in decreasing HPV infection and related diseases, such as warts and precancerous lesions. In this review, we present the updated information about current HPV vaccines, focusing on vaccine coverage and efficacy. In addition, pan-gender vaccination and current clinical trials are also discussed. Currently, more efforts should be put into increasing the vaccine’s coverage, especially in low- and middle-income countries. Provision of education on HPV and vaccination is one of the most important methods to achieve this. Vaccines that target HPV types not included in current vaccines are the next stage in vaccine development. In the future, all HPV-related cancers, such as head and neck cancer, and anal cancer, should be tracked and evaluated, especially in countries that have introduced pan-gender vaccination programs. Therapeutic vaccines, in combination with other cancer treatments, should continue to be investigated.https://www.mdpi.com/2076-393X/8/3/391human papillomavirusvaccineCervarixGardasilGardasil 9 |
spellingShingle | Liqin Cheng Yan Wang Juan Du Human Papillomavirus Vaccines: An Updated Review Vaccines human papillomavirus vaccine Cervarix Gardasil Gardasil 9 |
title | Human Papillomavirus Vaccines: An Updated Review |
title_full | Human Papillomavirus Vaccines: An Updated Review |
title_fullStr | Human Papillomavirus Vaccines: An Updated Review |
title_full_unstemmed | Human Papillomavirus Vaccines: An Updated Review |
title_short | Human Papillomavirus Vaccines: An Updated Review |
title_sort | human papillomavirus vaccines an updated review |
topic | human papillomavirus vaccine Cervarix Gardasil Gardasil 9 |
url | https://www.mdpi.com/2076-393X/8/3/391 |
work_keys_str_mv | AT liqincheng humanpapillomavirusvaccinesanupdatedreview AT yanwang humanpapillomavirusvaccinesanupdatedreview AT juandu humanpapillomavirusvaccinesanupdatedreview |