Seven Non-melanoma Features to Rule Out Facial Melanoma

Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesion...

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Main Authors: Philipp Tschandl, Alessio Gambardella, Amélie Boespflug, Teresa Deinlein, Vincenzo de Giorgi, Harald Kittler, Aimilios Lallas, Josep Malvehy, Elvira Moscarella, Susana Puig, Massimiliano Scalvenzi, Luc Thomas, Iris Zalaudek, Roberto Alfano, Giuseppe Argenziano
Format: Article
Language:English
Published: Medical Journals Sweden 2017-08-01
Series:Acta Dermato-Venereologica
Subjects:
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2759
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author Philipp Tschandl
Alessio Gambardella
Amélie Boespflug
Teresa Deinlein
Vincenzo de Giorgi
Harald Kittler
Aimilios Lallas
Josep Malvehy
Elvira Moscarella
Susana Puig
Massimiliano Scalvenzi
Luc Thomas
Iris Zalaudek
Roberto Alfano
Giuseppe Argenziano
author_facet Philipp Tschandl
Alessio Gambardella
Amélie Boespflug
Teresa Deinlein
Vincenzo de Giorgi
Harald Kittler
Aimilios Lallas
Josep Malvehy
Elvira Moscarella
Susana Puig
Massimiliano Scalvenzi
Luc Thomas
Iris Zalaudek
Roberto Alfano
Giuseppe Argenziano
author_sort Philipp Tschandl
collection DOAJ
description Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p < 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features.
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spelling doaj.art-24c7e253f87e43e4a1ce3944544977da2022-12-21T23:50:25ZengMedical Journals SwedenActa Dermato-Venereologica0001-55551651-20572017-08-0197101219122410.2340/00015555-27595035Seven Non-melanoma Features to Rule Out Facial MelanomaPhilipp Tschandl0Alessio GambardellaAmélie BoespflugTeresa DeinleinVincenzo de GiorgiHarald KittlerAimilios LallasJosep MalvehyElvira MoscarellaSusana PuigMassimiliano ScalvenziLuc ThomasIris ZalaudekRoberto AlfanoGiuseppe Argenziano Department of Dermatology, Medical University of Vienna, Wien, Austria. Facial melanoma is difficult to diagnose and dermatoscopic features are often subtle. Dermatoscopic non-melanoma patterns may have a comparable diagnostic value. In this pilot study, facial lesions were collected retrospectively, resulting in a case set of 339 melanomas and 308 non-melanomas. Lesions were evaluated for the prevalence (> 50% of lesional surface) of 7 dermatoscopic non-melanoma features: scales, white follicles, erythema/reticular vessels, reticular and/or curved lines/fingerprints, structureless brown colour, sharp demarcation, and classic criteria of seborrhoeic keratosis. Melanomas had a lower number of non-melanoma patterns (p < 0.001). Scoring a lesion suspicious when no prevalent non-melanoma pattern is found resulted in a sensitivity of 88.5% and a specificity of 66.9% for the diagnosis of melanoma. Specificity was higher for solar lentigo (78.8%) and seborrhoeic keratosis (74.3%) and lower for actinic keratosis (61.4%) and lichenoid keratosis (25.6%). Evaluation of prevalent non-melanoma patterns can provide slightly lower sensitivity and higher specificity in detecting facial melanoma compared with already known malignant features. https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2759 dermatoscopydermoscopyfacemelanomalentigomalignadiagnosis
spellingShingle Philipp Tschandl
Alessio Gambardella
Amélie Boespflug
Teresa Deinlein
Vincenzo de Giorgi
Harald Kittler
Aimilios Lallas
Josep Malvehy
Elvira Moscarella
Susana Puig
Massimiliano Scalvenzi
Luc Thomas
Iris Zalaudek
Roberto Alfano
Giuseppe Argenziano
Seven Non-melanoma Features to Rule Out Facial Melanoma
Acta Dermato-Venereologica
dermatoscopy
dermoscopy
face
melanoma
lentigomaligna
diagnosis
title Seven Non-melanoma Features to Rule Out Facial Melanoma
title_full Seven Non-melanoma Features to Rule Out Facial Melanoma
title_fullStr Seven Non-melanoma Features to Rule Out Facial Melanoma
title_full_unstemmed Seven Non-melanoma Features to Rule Out Facial Melanoma
title_short Seven Non-melanoma Features to Rule Out Facial Melanoma
title_sort seven non melanoma features to rule out facial melanoma
topic dermatoscopy
dermoscopy
face
melanoma
lentigomaligna
diagnosis
url https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2759
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