Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study
<p><strong>Introduction:</strong></p> <p>Trace elements are essential for normal metabolism. Their dysregulation adversely affects biological processes and may play a role in the pathogenesis of various diseases including schizophrenia. The role of micronutrients in sch...
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| Format: | Article |
| Language: | English |
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Sri Lanka College of Psychiatrists
2014-06-01
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| Series: | Sri Lanka Journal of Psychiatry |
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| Online Access: | https://sljpsyc.sljol.info/articles/7076 |
| _version_ | 1818436119089381376 |
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| author | Santosh K Sharma Sadhna Sood Atul Sharma I D Gupta |
| author_facet | Santosh K Sharma Sadhna Sood Atul Sharma I D Gupta |
| author_sort | Santosh K Sharma |
| collection | DOAJ |
| description | <p><strong>Introduction:</strong></p> <p>Trace elements are essential for normal metabolism. Their dysregulation adversely affects biological processes and may play a role in the pathogenesis of various diseases including schizophrenia. The role of micronutrients in schizophrenia has been investigated in a limited number of studies; the results are inconclusive.<strong> </strong></p> <p><strong> </strong></p> <p><strong>Aims:</strong></p> <p>To examine the serum levels of zinc and copper in patients with schizophrenia in comparison to healthy controls and also assess these levels in the acute and chronic stage of the illness</p> <p><strong> </strong></p> <p><strong>Method:</strong></p> <p>The study population comprised of 150 cases and 150 age-matched controls. Their serum zinc and copper levels were measured by an Atomic Absorption Spectrophotometer. Among the cases, the stage of illness was assessed using the Positive and Negative Syndrome Scale (PANSS) score.</p> <p><strong> </strong></p> <p><strong>Results:</strong></p> <p>The zinc and copper levels were higher significantly in patients with schizophrenia than in the control group.</p> <p><strong> </strong></p> <p><strong>Conclusion:</strong></p> <p>The evaluation of zinc and copper levels in patients with schizophrenia warrants further study.</p><p class="p0">DOI: <a href="http://dx.doi.org/10.4038/sljpsyc.v5i1.7076">http://dx.doi.org/10.4038/sljpsyc.v5i1.7076</a></p> <p>SL J Psychiatry 2014; 5 (1): 14-17</p> <p><strong> </strong></p> |
| first_indexed | 2024-12-14T17:03:42Z |
| format | Article |
| id | doaj.art-24caa8bface14c92bf6d2a59121da9a8 |
| institution | Directory Open Access Journal |
| issn | 2012-6883 2579-2008 |
| language | English |
| last_indexed | 2024-12-14T17:03:42Z |
| publishDate | 2014-06-01 |
| publisher | Sri Lanka College of Psychiatrists |
| record_format | Article |
| series | Sri Lanka Journal of Psychiatry |
| spelling | doaj.art-24caa8bface14c92bf6d2a59121da9a82022-12-21T22:53:46ZengSri Lanka College of PsychiatristsSri Lanka Journal of Psychiatry2012-68832579-20082014-06-0151141710.4038/sljpsyc.v5i1.70765397Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary studySantosh K Sharma0Sadhna Sood1Atul Sharma2I D GuptaSMS Medical College, JaipurSMS Medical College, JaipurGovernment Medical College, Jaipur<p><strong>Introduction:</strong></p> <p>Trace elements are essential for normal metabolism. Their dysregulation adversely affects biological processes and may play a role in the pathogenesis of various diseases including schizophrenia. The role of micronutrients in schizophrenia has been investigated in a limited number of studies; the results are inconclusive.<strong> </strong></p> <p><strong> </strong></p> <p><strong>Aims:</strong></p> <p>To examine the serum levels of zinc and copper in patients with schizophrenia in comparison to healthy controls and also assess these levels in the acute and chronic stage of the illness</p> <p><strong> </strong></p> <p><strong>Method:</strong></p> <p>The study population comprised of 150 cases and 150 age-matched controls. Their serum zinc and copper levels were measured by an Atomic Absorption Spectrophotometer. Among the cases, the stage of illness was assessed using the Positive and Negative Syndrome Scale (PANSS) score.</p> <p><strong> </strong></p> <p><strong>Results:</strong></p> <p>The zinc and copper levels were higher significantly in patients with schizophrenia than in the control group.</p> <p><strong> </strong></p> <p><strong>Conclusion:</strong></p> <p>The evaluation of zinc and copper levels in patients with schizophrenia warrants further study.</p><p class="p0">DOI: <a href="http://dx.doi.org/10.4038/sljpsyc.v5i1.7076">http://dx.doi.org/10.4038/sljpsyc.v5i1.7076</a></p> <p>SL J Psychiatry 2014; 5 (1): 14-17</p> <p><strong> </strong></p>https://sljpsyc.sljol.info/articles/7076zinccopperschizophrenia |
| spellingShingle | Santosh K Sharma Sadhna Sood Atul Sharma I D Gupta Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study Sri Lanka Journal of Psychiatry zinc copper schizophrenia |
| title | Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study |
| title_full | Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study |
| title_fullStr | Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study |
| title_full_unstemmed | Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study |
| title_short | Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study |
| title_sort | estimation of serum zinc and copper levels patients with schizophrenia a preliminary study |
| topic | zinc copper schizophrenia |
| url | https://sljpsyc.sljol.info/articles/7076 |
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