Primary lymphoma of the lumbar vertebrae: a case report and review of the literature

Abstract Background Primary lymphoma of the spinal vertebrae (PLSV) is an exceedingly rare disease with an unclear optimal treatment plan. We analyzed the clinical features of PLSV in the patient to strengthen our understanding of the disease and to review the literature. Case presentation A 65-year...

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Main Authors: Saeid Safaei, Parisa Azimi, Taravat Yazdanian, Saadat Molanaei
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Medical Case Reports
Subjects:
Online Access:https://doi.org/10.1186/s13256-022-03725-9
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author Saeid Safaei
Parisa Azimi
Taravat Yazdanian
Saadat Molanaei
author_facet Saeid Safaei
Parisa Azimi
Taravat Yazdanian
Saadat Molanaei
author_sort Saeid Safaei
collection DOAJ
description Abstract Background Primary lymphoma of the spinal vertebrae (PLSV) is an exceedingly rare disease with an unclear optimal treatment plan. We analyzed the clinical features of PLSV in the patient to strengthen our understanding of the disease and to review the literature. Case presentation A 65-year-old Persian man was admitted to our hospital with severe low back pain. The patient underwent radiological examinations including computed tomography (CT) scan, magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT). These examinations revealed a lesion in the L3 vertebra. Histological analysis showed a high-grade lymphoma. The patient underwent an L3 corpectomy with expandable cage placement, followed by an L2–L4 lateral screw placement with rod fixation. Also, facetectomy, laminectomy, and total spondylectomy were performed. Pedicle screws were inserted from L1 to L5. Titanium mesh was placed on the post-laminectomy defect. The treatment continued with local radiotherapy and chemotherapy. Post-treatment, the patient showed no new neurological deficit, and in the final follow-up, the patient had achieved a good recovery. Conclusion To our knowledge, no prior published literature has revealed a primary lymphoma of the lumbar vertebrae. Here, we report this case of PLSV for the first time and provide a brief review of the literature.
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spelling doaj.art-24cb12c098484a8c836fb62ece4617b52023-02-12T12:13:17ZengBMCJournal of Medical Case Reports1752-19472023-02-011711610.1186/s13256-022-03725-9Primary lymphoma of the lumbar vertebrae: a case report and review of the literatureSaeid Safaei0Parisa Azimi1Taravat Yazdanian2Saadat Molanaei3Knee and Sport Medicine Research Center, Milad General HospitalNeuroscience Research Center, Shahid Beheshti University of Medical SciencesSchool of Medicine, Capital Medical UniversityDepartment of Pathology, Milad General HospitalAbstract Background Primary lymphoma of the spinal vertebrae (PLSV) is an exceedingly rare disease with an unclear optimal treatment plan. We analyzed the clinical features of PLSV in the patient to strengthen our understanding of the disease and to review the literature. Case presentation A 65-year-old Persian man was admitted to our hospital with severe low back pain. The patient underwent radiological examinations including computed tomography (CT) scan, magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT). These examinations revealed a lesion in the L3 vertebra. Histological analysis showed a high-grade lymphoma. The patient underwent an L3 corpectomy with expandable cage placement, followed by an L2–L4 lateral screw placement with rod fixation. Also, facetectomy, laminectomy, and total spondylectomy were performed. Pedicle screws were inserted from L1 to L5. Titanium mesh was placed on the post-laminectomy defect. The treatment continued with local radiotherapy and chemotherapy. Post-treatment, the patient showed no new neurological deficit, and in the final follow-up, the patient had achieved a good recovery. Conclusion To our knowledge, no prior published literature has revealed a primary lymphoma of the lumbar vertebrae. Here, we report this case of PLSV for the first time and provide a brief review of the literature.https://doi.org/10.1186/s13256-022-03725-9Primary lymphomaL3 vertebraReview
spellingShingle Saeid Safaei
Parisa Azimi
Taravat Yazdanian
Saadat Molanaei
Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
Journal of Medical Case Reports
Primary lymphoma
L3 vertebra
Review
title Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
title_full Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
title_fullStr Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
title_full_unstemmed Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
title_short Primary lymphoma of the lumbar vertebrae: a case report and review of the literature
title_sort primary lymphoma of the lumbar vertebrae a case report and review of the literature
topic Primary lymphoma
L3 vertebra
Review
url https://doi.org/10.1186/s13256-022-03725-9
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AT parisaazimi primarylymphomaofthelumbarvertebraeacasereportandreviewoftheliterature
AT taravatyazdanian primarylymphomaofthelumbarvertebraeacasereportandreviewoftheliterature
AT saadatmolanaei primarylymphomaofthelumbarvertebraeacasereportandreviewoftheliterature