Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies

Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies

Successful drug delivery by mucoadhesive systems depends on the polymer type, which usually gets adherent on hydration. The intended polymers must sustain the association with biomembranes and preserve or accommodate the drug for an extended time. The majority of hydrophilic polymers tend to make we...

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Bibliographic Details
Main Authors: Waleed Y. Rizg, N. Raghavendra Naveen, Mallesh Kurakula, Awaji Y. Safhi, Samar S. Murshid, Rayan Y. Mushtaq, Walaa A. Abualsunun, Majed Alharbi, Rana B. Bakhaidar, Alshaimaa M. Almehmady, Ahmad Salawi, Adel Al Fatease, Khaled M. Hosny
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceuticals
Subjects:
sustainability of natural resources
microsphere
thiolation
mucoadhesion
glibenclamide
central composite design
Online Access:https://www.mdpi.com/1424-8247/15/4/491

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