The pattern of neonatal gastro-intestinal perforation in upper Egypt

Abstract Background Neonatal gastro-intestinal perforation [NGIP] is one of the major problems in pediatric surgical practice. Although the outcomes of neonatal surgery have improved markedly over the past decade the mortality rates of neonates with NGIP are still high. The aim of this study was to...

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Main Authors: Nezar Abd Elrouf Abo-Halawa, Mohamed Ahmed Negm, Mohamed Fathy
Format: Article
Language:English
Published: SpringerOpen 2020-06-01
Series:Annals of Pediatric Surgery
Subjects:
Online Access:http://link.springer.com/article/10.1186/s43159-020-00029-9
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author Nezar Abd Elrouf Abo-Halawa
Mohamed Ahmed Negm
Mohamed Fathy
author_facet Nezar Abd Elrouf Abo-Halawa
Mohamed Ahmed Negm
Mohamed Fathy
author_sort Nezar Abd Elrouf Abo-Halawa
collection DOAJ
description Abstract Background Neonatal gastro-intestinal perforation [NGIP] is one of the major problems in pediatric surgical practice. Although the outcomes of neonatal surgery have improved markedly over the past decade the mortality rates of neonates with NGIP are still high. The aim of this study was to present the possible etiological factors, clinical findings, and operative procedures of NIP in our locality. Results A total of 34 neonates with NGIP were included in this study. The median age at presentation was (15.8 ± 7.0 SD) days. The median interval between presentation and surgical interference was (2.0 ± 1.1 SD).Necrotizing enterocolitis [NEC] was the commonest cause of neonatal gastro-intestinal perforation. The commonest site of perforation was the colon [11cases]. The overall mortality rate was 11 cases [32.4%]. The main cause of mortality was neonatal NEC [6 cases]. Eight cases [40 %] died out of 20 cases which the interval between the presentation and interference were more than one day. Conclusions Neonatal gastro-intestinal perforations are still associated with high mortality rate in our institutions, and delayed diagnosis with increased interval between the presentation and surgical intervention are associated with increased mortality. In our locality, although NEC is the commonest cause of NGIP, the iatrogenic cause is relatively higher than reported.
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spelling doaj.art-24d0df72af6141629bf3fed6f713bd962022-12-22T02:02:17ZengSpringerOpenAnnals of Pediatric Surgery2090-53942020-06-011611610.1186/s43159-020-00029-9The pattern of neonatal gastro-intestinal perforation in upper EgyptNezar Abd Elrouf Abo-Halawa0Mohamed Ahmed Negm1Mohamed Fathy2Pediatric Surgery unit, Qena Faculty of Medicine, South Valley UniversityPediatric Surgery unit, Qena Faculty of Medicine, South Valley UniversityPediatric Surgery Unit, Faculty of Medicine, Minia UniversityAbstract Background Neonatal gastro-intestinal perforation [NGIP] is one of the major problems in pediatric surgical practice. Although the outcomes of neonatal surgery have improved markedly over the past decade the mortality rates of neonates with NGIP are still high. The aim of this study was to present the possible etiological factors, clinical findings, and operative procedures of NIP in our locality. Results A total of 34 neonates with NGIP were included in this study. The median age at presentation was (15.8 ± 7.0 SD) days. The median interval between presentation and surgical interference was (2.0 ± 1.1 SD).Necrotizing enterocolitis [NEC] was the commonest cause of neonatal gastro-intestinal perforation. The commonest site of perforation was the colon [11cases]. The overall mortality rate was 11 cases [32.4%]. The main cause of mortality was neonatal NEC [6 cases]. Eight cases [40 %] died out of 20 cases which the interval between the presentation and interference were more than one day. Conclusions Neonatal gastro-intestinal perforations are still associated with high mortality rate in our institutions, and delayed diagnosis with increased interval between the presentation and surgical intervention are associated with increased mortality. In our locality, although NEC is the commonest cause of NGIP, the iatrogenic cause is relatively higher than reported.http://link.springer.com/article/10.1186/s43159-020-00029-9Neonatal gastro-intestinal perforationNecrotizing enterocolitisPerforationUpper Egypt
spellingShingle Nezar Abd Elrouf Abo-Halawa
Mohamed Ahmed Negm
Mohamed Fathy
The pattern of neonatal gastro-intestinal perforation in upper Egypt
Annals of Pediatric Surgery
Neonatal gastro-intestinal perforation
Necrotizing enterocolitis
Perforation
Upper Egypt
title The pattern of neonatal gastro-intestinal perforation in upper Egypt
title_full The pattern of neonatal gastro-intestinal perforation in upper Egypt
title_fullStr The pattern of neonatal gastro-intestinal perforation in upper Egypt
title_full_unstemmed The pattern of neonatal gastro-intestinal perforation in upper Egypt
title_short The pattern of neonatal gastro-intestinal perforation in upper Egypt
title_sort pattern of neonatal gastro intestinal perforation in upper egypt
topic Neonatal gastro-intestinal perforation
Necrotizing enterocolitis
Perforation
Upper Egypt
url http://link.springer.com/article/10.1186/s43159-020-00029-9
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