Bone Mineral Density in Ankylosing Spondylitis
Ankylosing Spondylitis (AS), a chronic inflammatory rheumatic disease. One of the most frequent and important complications in these patients is osteoporosis. There are controversial studies on the correlation of osteoporosis and disease duration, activity and functional status. Twenty-one male and...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2003-12-01
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| Series: | Türk Osteoporoz Dergisi |
| Subjects: | |
| Online Access: | http://www.turkosteoporozdergisi.org/article_4192/Bone-Mineral-Density-In-Ankylosing-Spondylitis |
| _version_ | 1797910962669355008 |
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| author | Bahar Çakmak Hidayet Sarı |
| author_facet | Bahar Çakmak Hidayet Sarı |
| author_sort | Bahar Çakmak |
| collection | DOAJ |
| description | Ankylosing Spondylitis (AS), a chronic inflammatory rheumatic disease. One of the most frequent and important complications in these patients is osteoporosis. There are controversial studies on the correlation of osteoporosis and disease duration, activity and functional status.
Twenty-one male and five female patients diagnosed as AS according to Modified New York, ESSG( European Spondyloartropaties Study Group) and Amor criteria were included in this study.
Disease duration and age-sex of the patients was assessed. Patients with ankylosed lumbar spine in late stages of the disease were excluded. Bone mineral density (BMD) was measured by DEXA( Hologic) at lumbar and femoral neck regions. BASDAI was used for evaluation of disease activity and BASFI index for functional status evaluation.Correlation of BMD with disease duration, BASDAI and BASFI indexes was assessed.
BMD at lumbar spine and femoral neck regions was found to be osteoporotic in 11,5 % of the patients. In the lumbar region there was no correlation between BMD and disease duration, BASFI and BASDAI indexes. BMD values of femoral neck showed a weak inverse correlation with disease duration, while no correlation was found between BMD and BASFI and BASDAI.
As a conclusion in AS patients osteoporosis besides the disease itself many secondarily influence disease prognosis and complications. Therefore osteoporosis should be evaluated in the management and follow-up of AS patients. |
| first_indexed | 2024-04-10T11:32:50Z |
| format | Article |
| id | doaj.art-24d4e5b6360a4b9c976934cb79c05f73 |
| institution | Directory Open Access Journal |
| issn | 2147-2653 |
| language | English |
| last_indexed | 2024-04-10T11:32:50Z |
| publishDate | 2003-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Osteoporoz Dergisi |
| spelling | doaj.art-24d4e5b6360a4b9c976934cb79c05f732023-02-15T16:17:58ZengGalenos YayineviTürk Osteoporoz Dergisi2147-26532003-12-0194141145Bone Mineral Density in Ankylosing SpondylitisBahar Çakmak0Hidayet Sarı1İstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, İstanbul, Türkiyeİstanbul Üniversitesi Cerrahpaşa Tıp Fakültesi, Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı, İstanbul, TürkiyeAnkylosing Spondylitis (AS), a chronic inflammatory rheumatic disease. One of the most frequent and important complications in these patients is osteoporosis. There are controversial studies on the correlation of osteoporosis and disease duration, activity and functional status. Twenty-one male and five female patients diagnosed as AS according to Modified New York, ESSG( European Spondyloartropaties Study Group) and Amor criteria were included in this study. Disease duration and age-sex of the patients was assessed. Patients with ankylosed lumbar spine in late stages of the disease were excluded. Bone mineral density (BMD) was measured by DEXA( Hologic) at lumbar and femoral neck regions. BASDAI was used for evaluation of disease activity and BASFI index for functional status evaluation.Correlation of BMD with disease duration, BASDAI and BASFI indexes was assessed. BMD at lumbar spine and femoral neck regions was found to be osteoporotic in 11,5 % of the patients. In the lumbar region there was no correlation between BMD and disease duration, BASFI and BASDAI indexes. BMD values of femoral neck showed a weak inverse correlation with disease duration, while no correlation was found between BMD and BASFI and BASDAI. As a conclusion in AS patients osteoporosis besides the disease itself many secondarily influence disease prognosis and complications. Therefore osteoporosis should be evaluated in the management and follow-up of AS patients.http://www.turkosteoporozdergisi.org/article_4192/Bone-Mineral-Density-In-Ankylosing-SpondylitisASosteoporosisdisease activiy |
| spellingShingle | Bahar Çakmak Hidayet Sarı Bone Mineral Density in Ankylosing Spondylitis Türk Osteoporoz Dergisi AS osteoporosis disease activiy |
| title | Bone Mineral Density in Ankylosing Spondylitis |
| title_full | Bone Mineral Density in Ankylosing Spondylitis |
| title_fullStr | Bone Mineral Density in Ankylosing Spondylitis |
| title_full_unstemmed | Bone Mineral Density in Ankylosing Spondylitis |
| title_short | Bone Mineral Density in Ankylosing Spondylitis |
| title_sort | bone mineral density in ankylosing spondylitis |
| topic | AS osteoporosis disease activiy |
| url | http://www.turkosteoporozdergisi.org/article_4192/Bone-Mineral-Density-In-Ankylosing-Spondylitis |
| work_keys_str_mv | AT baharcakmak bonemineraldensityinankylosingspondylitis AT hidayetsarı bonemineraldensityinankylosingspondylitis |