Changing parameters immune system in children with different forms of early congenital syphilis

The results of immunological monitoring of 40 children with early congenital syphilis in the acute period and after specific therapy. Revealed that the severity of changes in the immune system depend on the clinical form of the disease and the most significant group of children with polisimptomnym o...

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Main Authors: G. P. Martynova, N. F. Kuznetsova
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/114
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author G. P. Martynova
N. F. Kuznetsova
author_facet G. P. Martynova
N. F. Kuznetsova
author_sort G. P. Martynova
collection DOAJ
description The results of immunological monitoring of 40 children with early congenital syphilis in the acute period and after specific therapy. Revealed that the severity of changes in the immune system depend on the clinical form of the disease and the most significant group of children with polisimptomnym over syphilitic infection. The majority of the investigated immunological parameters after specific therapy in patients of this group are not restored to control values, which can be regarded as serious, not smooth during desease. Babies with early monosemeiotic form of congenital syphilis immunological indicators partially recovered, indicating a possible protracted course of the process. At the same time, patients with latent form of the disease immunological parameters restored to control values, which suggesta favorable prognosis.
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spelling doaj.art-24d973d5303440b9ac7a053cb4b95f252025-03-02T13:00:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0143535710.22625/2072-6732-2012-4-3-53-57128Changing parameters immune system in children with different forms of early congenital syphilisG. P. Martynova0N. F. Kuznetsova1Krasnoyarsk state medical university named by professor V.F. Vojno-Yasenecky, KrasnoyarskKrasnoyarsk state medical university named by professor V.F. Vojno-Yasenecky, Krasnoyarsk City Children’s Clinical Hospital №1, KrasnoyarskThe results of immunological monitoring of 40 children with early congenital syphilis in the acute period and after specific therapy. Revealed that the severity of changes in the immune system depend on the clinical form of the disease and the most significant group of children with polisimptomnym over syphilitic infection. The majority of the investigated immunological parameters after specific therapy in patients of this group are not restored to control values, which can be regarded as serious, not smooth during desease. Babies with early monosemeiotic form of congenital syphilis immunological indicators partially recovered, indicating a possible protracted course of the process. At the same time, patients with latent form of the disease immunological parameters restored to control values, which suggesta favorable prognosis.https://journal.niidi.ru/jofin/article/view/114childrenan early congenital syphilisimmunological parameters
spellingShingle G. P. Martynova
N. F. Kuznetsova
Changing parameters immune system in children with different forms of early congenital syphilis
Журнал инфектологии
children
an early congenital syphilis
immunological parameters
title Changing parameters immune system in children with different forms of early congenital syphilis
title_full Changing parameters immune system in children with different forms of early congenital syphilis
title_fullStr Changing parameters immune system in children with different forms of early congenital syphilis
title_full_unstemmed Changing parameters immune system in children with different forms of early congenital syphilis
title_short Changing parameters immune system in children with different forms of early congenital syphilis
title_sort changing parameters immune system in children with different forms of early congenital syphilis
topic children
an early congenital syphilis
immunological parameters
url https://journal.niidi.ru/jofin/article/view/114
work_keys_str_mv AT gpmartynova changingparametersimmunesysteminchildrenwithdifferentformsofearlycongenitalsyphilis
AT nfkuznetsova changingparametersimmunesysteminchildrenwithdifferentformsofearlycongenitalsyphilis