Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient
Pseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-10-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340920309653 |
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| author | Prakhar Srivastava Sankaranarayanan Gomathinayagam Nalini Easwaran Gowri Sankar E. Padmavathi Manoharan Shankar Kodiveri M. Gothandam Karthikeyan Sivashanmugam |
| author_facet | Prakhar Srivastava Sankaranarayanan Gomathinayagam Nalini Easwaran Gowri Sankar E. Padmavathi Manoharan Shankar Kodiveri M. Gothandam Karthikeyan Sivashanmugam |
| author_sort | Prakhar Srivastava |
| collection | DOAJ |
| description | Pseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas aeruginosa isolates (VIT PC 7 and VIT PC 9) displaying homoserine lactone, rhamnolipid producing, biofilm phenotype and antibiotic resistance genes related to carbapenem, aminoglycoside, beta- lactamase and tetracycline resistance. The whole genome sequencing library was prepared according to the Oxford Nanopore's SQK-LSK108 kit protocol on Oxford Nanopore's Minion platform. The 7.1 Mb and 6.3-Mb draft genome sequence with GC content of 65.8% and 66.4% respectively provides insight into their resistance mechanism and virulence factors. |
| first_indexed | 2024-12-14T00:01:33Z |
| format | Article |
| id | doaj.art-24df33d4314a4e6bb453bc192bdd2f50 |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-14T00:01:33Z |
| publishDate | 2020-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-24df33d4314a4e6bb453bc192bdd2f502022-12-21T23:26:18ZengElsevierData in Brief2352-34092020-10-0132106071Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patientPrakhar Srivastava0Sankaranarayanan Gomathinayagam1Nalini Easwaran2Gowri Sankar3E. Padmavathi4Manoharan Shankar5Kodiveri M. Gothandam6Karthikeyan Sivashanmugam7School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaSchool of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaCorresponding author.; School of Bio Sciences and Technology, Vellore Institute of Technology, Vellore 632014 IndiaPseudomonas aeruginosa generally forms strong biofilm during chronic condition of wound. The whole mechanism of biofilm formation works in tandem with quorum sensing circuit of the organism in order to produce virulence. Here we report the draft genome sequence of two diabetic foot ulcer Pseudomonas aeruginosa isolates (VIT PC 7 and VIT PC 9) displaying homoserine lactone, rhamnolipid producing, biofilm phenotype and antibiotic resistance genes related to carbapenem, aminoglycoside, beta- lactamase and tetracycline resistance. The whole genome sequencing library was prepared according to the Oxford Nanopore's SQK-LSK108 kit protocol on Oxford Nanopore's Minion platform. The 7.1 Mb and 6.3-Mb draft genome sequence with GC content of 65.8% and 66.4% respectively provides insight into their resistance mechanism and virulence factors.http://www.sciencedirect.com/science/article/pii/S2352340920309653Diabetic foot ulcerBiofilmQuorum sensingHomoserine lactoneEfflux pump |
| spellingShingle | Prakhar Srivastava Sankaranarayanan Gomathinayagam Nalini Easwaran Gowri Sankar E. Padmavathi Manoharan Shankar Kodiveri M. Gothandam Karthikeyan Sivashanmugam Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient Data in Brief Diabetic foot ulcer Biofilm Quorum sensing Homoserine lactone Efflux pump |
| title | Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient |
| title_full | Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient |
| title_fullStr | Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient |
| title_full_unstemmed | Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient |
| title_short | Comparative data analsysis of two multi-drug resistant homoserine lactone and rhamnolipid producing Pseudomonas aeruginosa from diabetic foot infected patient |
| title_sort | comparative data analsysis of two multi drug resistant homoserine lactone and rhamnolipid producing pseudomonas aeruginosa from diabetic foot infected patient |
| topic | Diabetic foot ulcer Biofilm Quorum sensing Homoserine lactone Efflux pump |
| url | http://www.sciencedirect.com/science/article/pii/S2352340920309653 |
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