Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin

Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin

Abstract As novel mediators of cell‐to‐cell signalling, small extracellular vesicles (sEVs) play a critical role in physiological and pathophysiological processes. To date, the molecular mechanisms that support sEV generation are incompletely understood. Many kinases are reported for their roles in...

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Bibliographic Details
Main Authors: Yuefei Zhang, Yiqing Li, Pan Liu, Dacheng Gong, Hui Zhou, Wenjuan Li, Huilun Zhang, Wenfang Zheng, Jiaqi Xu, Hongqiang Cheng, Xue Zhang, Yuehai Ke
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Journal of Extracellular Vesicles
Subjects:
biogenesis
crosstalk
dephosphorylation
epithelial cells
macrophages
phosphatase
Online Access:https://doi.org/10.1002/jev2.12078

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