Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump
Introduction: Breast cancer is the commonest malignancy worldwide in women. Preoperative evaluation of breast lump plays a major role in the early diagnosis and management of the breast lesions. This study helps in subgrouping the breast lesions into various categories and provides the line of m...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2022-07-01
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| Series: | National Journal of Laboratory Medicine |
| Subjects: | |
| Online Access: | https://www.njlm.net/articles/PDF/2640/52142_CE[Ra1]_F(SHU)_PF1(AKA_SS)_PFA(SHU)_PB(AKA_SHU)_PN(SHU).pdf |
| _version_ | 1811179171581263872 |
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| author | Margaret Theresa Joseph Fathima Jackia Banu Gerard Rakesh |
| author_facet | Margaret Theresa Joseph Fathima Jackia Banu Gerard Rakesh |
| author_sort | Margaret Theresa Joseph |
| collection | DOAJ |
| description | Introduction: Breast cancer is the commonest malignancy
worldwide in women. Preoperative evaluation of breast lump
plays a major role in the early diagnosis and management of the
breast lesions. This study helps in subgrouping the breast lesions
into various categories and provides the line of management of
each category accordingly.
Aim: To evaluate the cytomorphology of various breast lesions,
to compare with histopathological findings and to assess the
usefulness of Modified Masood’s Scoring Index (MMSI) in
palpable breast lumps.
Materials and Methods: This was a cross-sectional study
done in 61 female patients who presented with palpable
breast lump between March 2019 and February 2021 at
the Pathology Department, Sri Venkateshwaraa Medical
College Hospital and Research Centre, Puducherry, India.
Cytological examination along with MMSI was applied on
Fine Needle Aspiration Cytology (FNAC) aspirates, followed
by histological confirmation. Under MMSI, the breast lesions
were categorised into four groups: Non Proliferative Breast
Disease (NPBD), PBD without atypia, PBD with atypia, and
carcinoma breast. The data were collected and compiled in
Microsoft Excel programme, appropriate graphs were made
and percentages were calculated.
Results: Total of 61 cases were analysed, females with age
range of 23 to 64 years, mean age of 38 years. Majority of the
cases presented with unilateral breast lump (92.5%). In MMSI,
15/61 (24.5%) were found with a score of 6 followed by 12/61
(19.6%) with a score of 8 which fell under NPBD. Of the total
number of cases, 2/61 (3.2%) had a score of 24, while 3/61
(4.9%) had a score of 23, which fell under carcinoma breast
category. Overall concordance observed between MMSI and
histopathology was 59/61 (96.72%) cases, which indicates the
high degree of concordance with histopathological diagnosis.
Conclusion: MMSI is a simple and reliable scoring system
and can be applied on FNAC aspirates. MMSI increases the
diagnostic accuracy and provides better concordance with
histopathology |
| first_indexed | 2024-04-11T06:31:25Z |
| format | Article |
| id | doaj.art-24e3c12ac55d414ba28e409a247d5b9b |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-04-11T06:31:25Z |
| publishDate | 2022-07-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-24e3c12ac55d414ba28e409a247d5b9b2022-12-22T04:40:03ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822022-07-01113363910.7860/NJLM/2022/52142.2640Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast LumpMargaret Theresa Joseph0Fathima Jackia Banu1Gerard Rakesh2Assistant Professor, Department of Pathology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Cuddalore OT (NM), Tamil Nadu, India. Postgraduate Student, Department of Pathology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Cuddalore OT (NM), Tamil Nadu, India.. Associate Professor, Department of Microbiology, Sri Venkateshwaraa Medical College Hospital and Research Centre, Cuddalore OT (NM), Tamil Nadu, IndiaIntroduction: Breast cancer is the commonest malignancy worldwide in women. Preoperative evaluation of breast lump plays a major role in the early diagnosis and management of the breast lesions. This study helps in subgrouping the breast lesions into various categories and provides the line of management of each category accordingly. Aim: To evaluate the cytomorphology of various breast lesions, to compare with histopathological findings and to assess the usefulness of Modified Masood’s Scoring Index (MMSI) in palpable breast lumps. Materials and Methods: This was a cross-sectional study done in 61 female patients who presented with palpable breast lump between March 2019 and February 2021 at the Pathology Department, Sri Venkateshwaraa Medical College Hospital and Research Centre, Puducherry, India. Cytological examination along with MMSI was applied on Fine Needle Aspiration Cytology (FNAC) aspirates, followed by histological confirmation. Under MMSI, the breast lesions were categorised into four groups: Non Proliferative Breast Disease (NPBD), PBD without atypia, PBD with atypia, and carcinoma breast. The data were collected and compiled in Microsoft Excel programme, appropriate graphs were made and percentages were calculated. Results: Total of 61 cases were analysed, females with age range of 23 to 64 years, mean age of 38 years. Majority of the cases presented with unilateral breast lump (92.5%). In MMSI, 15/61 (24.5%) were found with a score of 6 followed by 12/61 (19.6%) with a score of 8 which fell under NPBD. Of the total number of cases, 2/61 (3.2%) had a score of 24, while 3/61 (4.9%) had a score of 23, which fell under carcinoma breast category. Overall concordance observed between MMSI and histopathology was 59/61 (96.72%) cases, which indicates the high degree of concordance with histopathological diagnosis. Conclusion: MMSI is a simple and reliable scoring system and can be applied on FNAC aspirates. MMSI increases the diagnostic accuracy and provides better concordance with histopathologyhttps://www.njlm.net/articles/PDF/2640/52142_CE[Ra1]_F(SHU)_PF1(AKA_SS)_PFA(SHU)_PB(AKA_SHU)_PN(SHU).pdfbenign tumourbreast masscytomorphologyfine needle aspiration cytologymalignant tumourmodified masood’s scoring index |
| spellingShingle | Margaret Theresa Joseph Fathima Jackia Banu Gerard Rakesh Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump National Journal of Laboratory Medicine benign tumour breast mass cytomorphology fine needle aspiration cytology malignant tumour modified masood’s scoring index |
| title | Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump |
| title_full | Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump |
| title_fullStr | Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump |
| title_full_unstemmed | Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump |
| title_short | Evaluation of Cytological Scoring and Comparison with Histopathological Finding in a Palpable Breast Lump |
| title_sort | evaluation of cytological scoring and comparison with histopathological finding in a palpable breast lump |
| topic | benign tumour breast mass cytomorphology fine needle aspiration cytology malignant tumour modified masood’s scoring index |
| url | https://www.njlm.net/articles/PDF/2640/52142_CE[Ra1]_F(SHU)_PF1(AKA_SS)_PFA(SHU)_PB(AKA_SHU)_PN(SHU).pdf |
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