Generation of a new therapeutic d-peptide that induces the differentiation of acute myeloid leukemia cells through A TLR-2 signaling pathway

Generation of a new therapeutic d-peptide that induces the differentiation of acute myeloid leukemia cells through A TLR-2 signaling pathway

Abstract Acute myeloid leukemia (AML) is caused by clonal disorders of hematopoietic stem cells. Differentiation therapy is emerging as an important treatment modality for leukemia, given its less toxicity and wider applicable population, but the arsenal of differentiation-inducing agents is still v...

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Bibliographic Details
Main Authors: Fei Yu, Yingshi Chen, Mo Zhou, Lingling Liu, Bingfeng Liu, Jun Liu, Ting Pan, Yuewen Luo, Xu Zhang, Hailan Ou, Wenjing Huang, Xi Lv, Zhihui Xi, Ruozhi Xiao, Wenyu Li, Lixue Cao, Xiancai Ma, Jingwen Zhang, Lijuan Lu, Hui Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01822-w

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