Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China
Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in Shanghai, China. In a cohort study within Shang...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-11-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | http://dx.doi.org/10.1080/21645515.2022.2043025 |
| _version_ | 1827806455185539072 |
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| author | Mengdi Ji Zhuoying Huang Jia Ren Abram L. Wagner |
| author_facet | Mengdi Ji Zhuoying Huang Jia Ren Abram L. Wagner |
| author_sort | Mengdi Ji |
| collection | DOAJ |
| description | Given increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in Shanghai, China. In a cohort study within Shanghai, China, we ascertained vaccine hesitancy among parents of young infants, and later abstracted their childʻs electronic immunization records. We measure full coverage of vaccines on the mandatory, and publicly funded Expanded Program on Immunization (EPI). Non-EPI vaccines included pneumococcal conjugate vaccine, Haemophilus influenzae type b vaccine, and rotavirus vaccine. Vaccine hesitancy was linked to vaccine uptake through mixed effects logistic regression models. Among 972 children, full coverage of all EPI vaccines by 15 months was 95%, compared to dose 1 coverage of pneumococcal conjugate vaccine at 13%, Haemophilus influenzae type b vaccine at 68%, and rotavirus vaccine at 52%. Vaccine hesitancy was not significantly linked with full coverage of all EPI vaccines (OR: 1.55, 95% CI: .89, 2.72), but coverage in the vaccine hesitant was lower for pneumococcal conjugate vaccine dose 1 (OR: .70, 95% CI: .53, .91), and rotavirus vaccine dose 1 (OR: .69, 95% CI: .56, .86). Disparities by education level were not significant for EPI vaccines, but were for dose 1 of pneumococcal conjugate vaccine rotavirus vaccine. Overall, vaccine hesitancy was related to lower uptake of non-EPI, but not EPI vaccines. Shanghai has a robust system for insurance equitable access to EPI vaccines, but if vaccine hesitancy grows, it could reduce coverage of non-EPI vaccines. |
| first_indexed | 2024-03-11T21:41:24Z |
| format | Article |
| id | doaj.art-24e7edb29fe44664b6a1e42a3430fed5 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T21:41:24Z |
| publishDate | 2022-11-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-24e7edb29fe44664b6a1e42a3430fed52023-09-26T13:19:05ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-11-0118510.1080/21645515.2022.20430252043025Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, ChinaMengdi Ji0Zhuoying Huang1Jia Ren2Abram L. Wagner3University of MichiganShanghai Municipal Centers for Disease Control & PreventionShanghai Municipal Centers for Disease Control & PreventionUniversity of MichiganGiven increased global concern about vaccine hesitancy, this study estimates coverage of mandatory vs non-mandatory vaccines in children, and assesses whether vaccine hesitancy among young parents relates to their childʻs eventual vaccination status in Shanghai, China. In a cohort study within Shanghai, China, we ascertained vaccine hesitancy among parents of young infants, and later abstracted their childʻs electronic immunization records. We measure full coverage of vaccines on the mandatory, and publicly funded Expanded Program on Immunization (EPI). Non-EPI vaccines included pneumococcal conjugate vaccine, Haemophilus influenzae type b vaccine, and rotavirus vaccine. Vaccine hesitancy was linked to vaccine uptake through mixed effects logistic regression models. Among 972 children, full coverage of all EPI vaccines by 15 months was 95%, compared to dose 1 coverage of pneumococcal conjugate vaccine at 13%, Haemophilus influenzae type b vaccine at 68%, and rotavirus vaccine at 52%. Vaccine hesitancy was not significantly linked with full coverage of all EPI vaccines (OR: 1.55, 95% CI: .89, 2.72), but coverage in the vaccine hesitant was lower for pneumococcal conjugate vaccine dose 1 (OR: .70, 95% CI: .53, .91), and rotavirus vaccine dose 1 (OR: .69, 95% CI: .56, .86). Disparities by education level were not significant for EPI vaccines, but were for dose 1 of pneumococcal conjugate vaccine rotavirus vaccine. Overall, vaccine hesitancy was related to lower uptake of non-EPI, but not EPI vaccines. Shanghai has a robust system for insurance equitable access to EPI vaccines, but if vaccine hesitancy grows, it could reduce coverage of non-EPI vaccines.http://dx.doi.org/10.1080/21645515.2022.2043025longitudinal studiesrotavirus vaccineshaemophilus influenzae vaccinespneumococcal vaccine |
| spellingShingle | Mengdi Ji Zhuoying Huang Jia Ren Abram L. Wagner Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China Human Vaccines & Immunotherapeutics longitudinal studies rotavirus vaccines haemophilus influenzae vaccines pneumococcal vaccine |
| title | Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China |
| title_full | Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China |
| title_fullStr | Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China |
| title_full_unstemmed | Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China |
| title_short | Vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in Shanghai, China |
| title_sort | vaccine hesitancy and receipt of mandatory and optional pediatric vaccines in shanghai china |
| topic | longitudinal studies rotavirus vaccines haemophilus influenzae vaccines pneumococcal vaccine |
| url | http://dx.doi.org/10.1080/21645515.2022.2043025 |
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