CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy
Breast cancer has a high risk of metastasis; however, no effective treatment has been established. We developed a novel immunotherapy for breast cancer to enhance cytotoxic T lymphocytes against cancer cells using N1-type neutrophils with anti-tumor properties. For this purpose, we combined CXCL2 (C...
Main Authors: | Yi Chun Pan, Tomoyuki Nishikawa, Chin Yang Chang, Jiayu A. Tai, Yasufumi Kaneda |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-03-01
|
Series: | Molecular Therapy: Oncolytics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2372770520301856 |
Similar Items
-
Boron-incorporating hemagglutinating virus of Japan envelope (HVJ-E) nanomaterial in boron neutron capture therapy
by: Shuichiro Yoneoka, et al.
Published: (2019-12-01) -
The PD-L1/PD-1 Axis Blocks Neutrophil Cytotoxicity in Cancer
by: Olga Yajuk, et al.
Published: (2021-06-01) -
Unexpected curative effect of PD-1 inhibitor in gastric cancer with brain metastasis: A case report
by: Qijun Wang, et al.
Published: (2023-02-01) -
Progress of Immunotherapy Mechanisms and Current Evidence of PD-1/PD-L1
Checkpoint Inhibitors for Non-small Cell Lung Cancer with Brain Metastasis
by: Jiamin SHENG, et al.
Published: (2020-11-01) -
Programmed Death-Ligand 1 as a Regulator of Tumor Progression and Metastasis
by: Ioannis A. Vathiotis, et al.
Published: (2021-05-01)