Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri
OBJECTIVE: Pseudotumor cerebri (PC) or idiopathic benign intracranial hypertension is characterized by abnormal elevation of intracranial pressure with a normal composition of the cerebrospinal fluid (CSF) and absence of hydrocephaly or any intracranial mass lesion. Papilledema is the major clin...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2006-02-01
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| Series: | Türk Nöroloji Dergisi |
| Subjects: | |
| Online Access: | https://www.journalagent.com/tjn/pdfs/TJN_12_1_25_29.pdf |
| _version_ | 1797912048805347328 |
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| author | Şebnem Bıçakçı Kenan Bıçakçı Kezban Aslan Hacer Bozdemir Cansel Karayalçın Yakup Sarıca |
| author_facet | Şebnem Bıçakçı Kenan Bıçakçı Kezban Aslan Hacer Bozdemir Cansel Karayalçın Yakup Sarıca |
| author_sort | Şebnem Bıçakçı |
| collection | DOAJ |
| description | OBJECTIVE: Pseudotumor cerebri (PC) or idiopathic benign
intracranial hypertension is characterized by abnormal elevation of
intracranial pressure with a normal composition of the cerebrospinal
fluid (CSF) and absence of hydrocephaly or any intracranial mass lesion.
Papilledema is the major clinical finding whereas neuroradiological
imaging findings are almost always normal
METHODS: In this preliminary study, we aimed to find out whether
diffusion and perfusion magnetic resonance (MR) imaging in PC patients
might be beneficial in the diagnosis.
RESULTS: We prospectively evaluated diffusion and perfusion MR
findings of 10 PC patients and 10 normal control group. On physical
examination, all PC patients had characteristic papilledema, varying
degrees of headache, blurred vision and tinnitus. Cerebrospinal fluid
(CSF) pressure was higher than 250mm H2O in all patients. MR imaging
was performed with a 1.5 tesla equipment and postprocess analyses
were done on an independent workstation.
There were no diffusion abnormalities in CP patients or differences
when compared to normal group. Perfusion abnormal ities were
detected in seven patients.
CONCLUSION: Pseudotumor cerebri is a clinical syndrome which requires prompt diagnosis and thorough evaluation. Treatment is crucial for
preventing visual loss and improving associated symptoms. Since
majority of the patients lack specific neuroradiological imaging findings,
the syndrome is mostly diagnosed based on the clinical findings.
Probably due to the latter factor, there is almost no major paper in the
literature concerning the neuroradiologic aspects of the syndrome.
Although our patient series is very limited for statistical evaluation,
broader series might put forward additional benefit of perfusion MR
imaging in diagnosis of pseudotumor cerebri |
| first_indexed | 2024-04-10T11:50:16Z |
| format | Article |
| id | doaj.art-24f0a83005d2411d90503d8d18010ef1 |
| institution | Directory Open Access Journal |
| issn | 1301-062X 1309-2545 |
| language | English |
| last_indexed | 2024-04-10T11:50:16Z |
| publishDate | 2006-02-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Nöroloji Dergisi |
| spelling | doaj.art-24f0a83005d2411d90503d8d18010ef12023-02-15T16:17:09ZengGalenos YayineviTürk Nöroloji Dergisi1301-062X1309-25452006-02-011212529Diffusion Perfusion MRI in Idiopathic Pseudotumor CerebriŞebnem Bıçakçı0Kenan Bıçakçı1Kezban Aslan2Hacer Bozdemir3Cansel Karayalçın4Yakup Sarıca5Department Of Neurology, Cukurova University, Faculty Of Medicine, Adana, TurkeyDepartment Of Radiology, Cukurova University, Faculty Of Medicine, Adana, TurkeyDepartment Of Neurology, Cukurova University, Faculty Of Medicine, Adana, TurkeyDepartment Of Neurology, Cukurova University, Faculty Of Medicine, Adana, TurkeyDepartment Of Neurology, Cukurova University, Faculty Of Medicine, Adana, TurkeyDepartment Of Neurology, Cukurova University, Faculty Of Medicine, Adana, TurkeyOBJECTIVE: Pseudotumor cerebri (PC) or idiopathic benign intracranial hypertension is characterized by abnormal elevation of intracranial pressure with a normal composition of the cerebrospinal fluid (CSF) and absence of hydrocephaly or any intracranial mass lesion. Papilledema is the major clinical finding whereas neuroradiological imaging findings are almost always normal METHODS: In this preliminary study, we aimed to find out whether diffusion and perfusion magnetic resonance (MR) imaging in PC patients might be beneficial in the diagnosis. RESULTS: We prospectively evaluated diffusion and perfusion MR findings of 10 PC patients and 10 normal control group. On physical examination, all PC patients had characteristic papilledema, varying degrees of headache, blurred vision and tinnitus. Cerebrospinal fluid (CSF) pressure was higher than 250mm H2O in all patients. MR imaging was performed with a 1.5 tesla equipment and postprocess analyses were done on an independent workstation. There were no diffusion abnormalities in CP patients or differences when compared to normal group. Perfusion abnormal ities were detected in seven patients. CONCLUSION: Pseudotumor cerebri is a clinical syndrome which requires prompt diagnosis and thorough evaluation. Treatment is crucial for preventing visual loss and improving associated symptoms. Since majority of the patients lack specific neuroradiological imaging findings, the syndrome is mostly diagnosed based on the clinical findings. Probably due to the latter factor, there is almost no major paper in the literature concerning the neuroradiologic aspects of the syndrome. Although our patient series is very limited for statistical evaluation, broader series might put forward additional benefit of perfusion MR imaging in diagnosis of pseudotumor cerebrihttps://www.journalagent.com/tjn/pdfs/TJN_12_1_25_29.pdfpseudotumor cerebridiffusion MRIperfusion MRI |
| spellingShingle | Şebnem Bıçakçı Kenan Bıçakçı Kezban Aslan Hacer Bozdemir Cansel Karayalçın Yakup Sarıca Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri Türk Nöroloji Dergisi pseudotumor cerebri diffusion MRI perfusion MRI |
| title | Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri |
| title_full | Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri |
| title_fullStr | Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri |
| title_full_unstemmed | Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri |
| title_short | Diffusion Perfusion MRI in Idiopathic Pseudotumor Cerebri |
| title_sort | diffusion perfusion mri in idiopathic pseudotumor cerebri |
| topic | pseudotumor cerebri diffusion MRI perfusion MRI |
| url | https://www.journalagent.com/tjn/pdfs/TJN_12_1_25_29.pdf |
| work_keys_str_mv | AT sebnembıcakcı diffusionperfusionmriinidiopathicpseudotumorcerebri AT kenanbıcakcı diffusionperfusionmriinidiopathicpseudotumorcerebri AT kezbanaslan diffusionperfusionmriinidiopathicpseudotumorcerebri AT hacerbozdemir diffusionperfusionmriinidiopathicpseudotumorcerebri AT canselkarayalcın diffusionperfusionmriinidiopathicpseudotumorcerebri AT yakupsarıca diffusionperfusionmriinidiopathicpseudotumorcerebri |