Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era

Owing to uncharacteristic initial symptoms and rapid progression, invasive meningococcal disease is still a challenge to diagnose and treat, even in high-income countries. Waterhouse-Friderichsen syndrome is a potentially fatal complication of invasive meningococcal disease, presenting as acute adre...

Full description

Bibliographic Details
Main Authors: Marta Serafin, Ewa Czerwińska, Marian Koźbiał, Mariusz Leszczyński, Leszek Szenborn
Format: Article
Language:English
Published: Termedia Publishing House 2023-03-01
Series:Pediatria Polska
Subjects:
Online Access:https://www.termedia.pl/Fatal-Waterhouse-Friderichsen-syndrome-due-to-Neisseria-r-nmeningitidis-group-B-in-a-paediatric-patient-during-r-nthe-phone-consultation-era,127,50139,1,1.html
_version_ 1797215342850736128
author Marta Serafin
Ewa Czerwińska
Marian Koźbiał
Mariusz Leszczyński
Leszek Szenborn
author_facet Marta Serafin
Ewa Czerwińska
Marian Koźbiał
Mariusz Leszczyński
Leszek Szenborn
author_sort Marta Serafin
collection DOAJ
description Owing to uncharacteristic initial symptoms and rapid progression, invasive meningococcal disease is still a challenge to diagnose and treat, even in high-income countries. Waterhouse-Friderichsen syndrome is a potentially fatal complication of invasive meningococcal disease, presenting as acute adrenal insufficiency due to haemorrhagic necrosis of the adrenal glands. We report a case of 5.5-year-old boy who presented to the hospital with fever, impaired consciousness, vomiting, and upper respiratory tract infection symptoms. Despite prompt diagnosis of invasive disease and adequate treatment, the patient died. We underline the need to increase parents’ knowledge and better access to vaccines against meningococci for Polish paediatric patients. Paediatricians and primary care physicians must remain alert and be ready to suspect invasive meningococcal disease in their patients.
first_indexed 2024-04-24T11:28:33Z
format Article
id doaj.art-24f0e2828ad64a558020415134c3ab88
institution Directory Open Access Journal
issn 0031-3939
2300-8660
language English
last_indexed 2024-04-24T11:28:33Z
publishDate 2023-03-01
publisher Termedia Publishing House
record_format Article
series Pediatria Polska
spelling doaj.art-24f0e2828ad64a558020415134c3ab882024-04-10T12:40:19ZengTermedia Publishing HousePediatria Polska0031-39392300-86602023-03-01981747810.5114/polp.2023.12506350139Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation eraMarta SerafinEwa CzerwińskaMarian KoźbiałMariusz LeszczyńskiLeszek SzenbornOwing to uncharacteristic initial symptoms and rapid progression, invasive meningococcal disease is still a challenge to diagnose and treat, even in high-income countries. Waterhouse-Friderichsen syndrome is a potentially fatal complication of invasive meningococcal disease, presenting as acute adrenal insufficiency due to haemorrhagic necrosis of the adrenal glands. We report a case of 5.5-year-old boy who presented to the hospital with fever, impaired consciousness, vomiting, and upper respiratory tract infection symptoms. Despite prompt diagnosis of invasive disease and adequate treatment, the patient died. We underline the need to increase parents’ knowledge and better access to vaccines against meningococci for Polish paediatric patients. Paediatricians and primary care physicians must remain alert and be ready to suspect invasive meningococcal disease in their patients.https://www.termedia.pl/Fatal-Waterhouse-Friderichsen-syndrome-due-to-Neisseria-r-nmeningitidis-group-B-in-a-paediatric-patient-during-r-nthe-phone-consultation-era,127,50139,1,1.htmlbacterial meningitis preventive vaccinations invasive meningococcal disease waterhouse-friderichsen syndrome
spellingShingle Marta Serafin
Ewa Czerwińska
Marian Koźbiał
Mariusz Leszczyński
Leszek Szenborn
Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
Pediatria Polska
bacterial meningitis
preventive vaccinations
invasive meningococcal disease
waterhouse-friderichsen syndrome
title Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
title_full Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
title_fullStr Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
title_full_unstemmed Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
title_short Fatal Waterhouse-Friderichsen syndrome due to Neisseria meningitidis group B in a paediatric patient during the phone consultation era
title_sort fatal waterhouse friderichsen syndrome due to neisseria meningitidis group b in a paediatric patient during the phone consultation era
topic bacterial meningitis
preventive vaccinations
invasive meningococcal disease
waterhouse-friderichsen syndrome
url https://www.termedia.pl/Fatal-Waterhouse-Friderichsen-syndrome-due-to-Neisseria-r-nmeningitidis-group-B-in-a-paediatric-patient-during-r-nthe-phone-consultation-era,127,50139,1,1.html
work_keys_str_mv AT martaserafin fatalwaterhousefriderichsensyndromeduetoneisseriameningitidisgroupbinapaediatricpatientduringthephoneconsultationera
AT ewaczerwinska fatalwaterhousefriderichsensyndromeduetoneisseriameningitidisgroupbinapaediatricpatientduringthephoneconsultationera
AT mariankozbiał fatalwaterhousefriderichsensyndromeduetoneisseriameningitidisgroupbinapaediatricpatientduringthephoneconsultationera
AT mariuszleszczynski fatalwaterhousefriderichsensyndromeduetoneisseriameningitidisgroupbinapaediatricpatientduringthephoneconsultationera
AT leszekszenborn fatalwaterhousefriderichsensyndromeduetoneisseriameningitidisgroupbinapaediatricpatientduringthephoneconsultationera