Comparison of Manual and Semi-Automatic [18F]PSMA-1007 PET Based Contouring Techniques for Intraprostatic Tumor Delineation in Patients With Primary Prostate Cancer and Validation With Histopathology as Standard of Reference

Comparison of Manual and Semi-Automatic [18F]PSMA-1007 PET Based Contouring Techniques for Intraprostatic Tumor Delineation in Patients With Primary Prostate Cancer and Validation With Histopathology as Standard of Reference

PurposeAccurate contouring of intraprostatic gross tumor volume (GTV) is pivotal for successful delivery of focal therapies and for biopsy guidance in patients with primary prostate cancer (PCa). Contouring of GTVs, using 18-Fluor labeled tracer prostate specific membrane antigen positron emission t...

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Bibliographic Details
Main Authors: Simon K. B. Spohn, Maria Kramer, Selina Kiefer, Peter Bronsert, August Sigle, Wolfgang Schultze-Seemann, Cordula A. Jilg, Tanja Sprave, Lara Ceci, Thomas F. Fassbender, Nils H. Nicolay, Juri Ruf, Anca L. Grosu, Constantinos Zamboglou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
primary prostate cancer
focal therapy
contouring
PSMA-PET/CT
histopathology
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.600690/full

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