Restraint stress during neonatal hypoxia‐ischemia alters brain injury following normothermia and hypothermia

Abstract Rodent models of neonatal hypoxic–ischemic (HI) injury require a subset of animals to be immobilized for continuous temperature monitoring during the insult and subsequent treatment. Restrained animals are discarded from the analysis due to the effect of restraint on the brain injury as fir...

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Bibliographic Details
Main Authors: Julia K. Gundersen, Hemmen Sabir, Thomas R. Wood, Damjan Osredkar, Mari Falck, Else M. Loeberg, Lars Walloe, David A. Menassa, Marianne Thoresen
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15562