Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein.

Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein.

Development of multidrug resistance (MDR) is a continuous clinical challenge partially due to the overexpression of P-glycoprotein (P-gp) for chronic myelogenous leukemia (CML) patients. Herein, we evaluated the inhibitory potency of emodin, a natural anthraquinone derivative isolated from Rheum pal...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Hongping Min, Miaomiao Niu, Weilin Zhang, Jia Yan, Jiachang Li, Xiying Tan, Bo Li, Mengxiang Su, Bin Di, Fang Yan
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science (PLoS) 2017-01-01
Цуврал:	PLoS ONE
Онлайн хандалт:	http://europepmc.org/articles/PMC5679605?pdf=render

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