Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study

Impact of Pre-Analytical Factors on MSI Test Accuracy in Mucinous Colorectal Adenocarcinoma: A Multi-Assay Concordance Study

Immunohistochemistry (IHC) and polymerase chain reaction (PCR) and fragment separation by capillary electrophoresis represent the current clinical laboratory standard for the evaluation of microsatellite instability (MSI) status. The importance of reporting MSI status in colorectal cancer is based o...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Umberto Malapelle, Paola Parente, Francesco Pepe, Caterina De Luca, Pellegrino Cerino, Claudia Covelli, Mariangela Balestrieri, Gianluca Russo, Antonio Bonfitto, Pasquale Pisapia, Fabiola Fiordelisi, Maria D’Armiento, Dario Bruzzese, Fotios Loupakis, Filippo Pietrantonio, Maria Triassi, Matteo Fassan, Giancarlo Troncone, Paolo Graziano
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2020-09-01
Schriftenreihe:Cells
Schlagworte:
predictive molecular pathology
IHC
fully automated RT—PCR
microfluidic
mCRC
Online Zugang:https://www.mdpi.com/2073-4409/9/9/2019

Online

https://www.mdpi.com/2073-4409/9/9/2019

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