Powassan virus infection: case series and literature review from a single institution

<p>Abstract</p> <p>Background</p> <p>Powassan virus is a flavivirus related to eastern hemisphere’s tick-borne encephalitis viruses. It can cause a rare but potentially life-threatening disease including encephalitis.</p> <p>Case presentation</p> <p...

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Main Authors: Raval Mihir, Singhal Mayank, Guerrero Dubert, Alonto Augusto
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Research Notes
Subjects:
Online Access:http://www.biomedcentral.com/1756-0500/5/594
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author Raval Mihir
Singhal Mayank
Guerrero Dubert
Alonto Augusto
author_facet Raval Mihir
Singhal Mayank
Guerrero Dubert
Alonto Augusto
author_sort Raval Mihir
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Powassan virus is a flavivirus related to eastern hemisphere’s tick-borne encephalitis viruses. It can cause a rare but potentially life-threatening disease including encephalitis.</p> <p>Case presentation</p> <p>We report four cases of POWV infection in Minnesota and North Dakota with known exposure to tick bites in 2011. Our first case was an 18-year-old male who dramatically presented with seizure and headache with positive serum analysis for Powassan virus immunoglobulin M. The second case was a 60 year old gentleman with intraparenchymal hemorrhage and was diagnosed via cerebrospinal fluid analysis. Thirdly, a 61 year old male developed altered mental status and encephalitis. Our fourth patient was a 69 year old male who had headache and non-focal weakness who was diagnosed with serum analysis.</p> <p>Conclusion</p> <p>Symptoms of Powassan virus infection ranged from headaches to seizures and severe neurological symptoms. This study serves to highlight the increased detection of Powassan virus infection in the central north United States. This report focuses on the increasing incidence that can lead to increasing efforts for raising awareness regarding this infection. There is a need for clinician vigilance and public attention due to its increasing detection, westward progression and varied clinical presentations.</p>
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spelling doaj.art-24f88fc7caec43068cae87dbcba8ddca2022-12-21T20:56:08ZengBMCBMC Research Notes1756-05002012-10-015159410.1186/1756-0500-5-594Powassan virus infection: case series and literature review from a single institutionRaval MihirSinghal MayankGuerrero DubertAlonto Augusto<p>Abstract</p> <p>Background</p> <p>Powassan virus is a flavivirus related to eastern hemisphere’s tick-borne encephalitis viruses. It can cause a rare but potentially life-threatening disease including encephalitis.</p> <p>Case presentation</p> <p>We report four cases of POWV infection in Minnesota and North Dakota with known exposure to tick bites in 2011. Our first case was an 18-year-old male who dramatically presented with seizure and headache with positive serum analysis for Powassan virus immunoglobulin M. The second case was a 60 year old gentleman with intraparenchymal hemorrhage and was diagnosed via cerebrospinal fluid analysis. Thirdly, a 61 year old male developed altered mental status and encephalitis. Our fourth patient was a 69 year old male who had headache and non-focal weakness who was diagnosed with serum analysis.</p> <p>Conclusion</p> <p>Symptoms of Powassan virus infection ranged from headaches to seizures and severe neurological symptoms. This study serves to highlight the increased detection of Powassan virus infection in the central north United States. This report focuses on the increasing incidence that can lead to increasing efforts for raising awareness regarding this infection. There is a need for clinician vigilance and public attention due to its increasing detection, westward progression and varied clinical presentations.</p>http://www.biomedcentral.com/1756-0500/5/594Powassan Virus encephalitisTick borne encephalitisIntraparenchymal hemorrhageSeizures
spellingShingle Raval Mihir
Singhal Mayank
Guerrero Dubert
Alonto Augusto
Powassan virus infection: case series and literature review from a single institution
BMC Research Notes
Powassan Virus encephalitis
Tick borne encephalitis
Intraparenchymal hemorrhage
Seizures
title Powassan virus infection: case series and literature review from a single institution
title_full Powassan virus infection: case series and literature review from a single institution
title_fullStr Powassan virus infection: case series and literature review from a single institution
title_full_unstemmed Powassan virus infection: case series and literature review from a single institution
title_short Powassan virus infection: case series and literature review from a single institution
title_sort powassan virus infection case series and literature review from a single institution
topic Powassan Virus encephalitis
Tick borne encephalitis
Intraparenchymal hemorrhage
Seizures
url http://www.biomedcentral.com/1756-0500/5/594
work_keys_str_mv AT ravalmihir powassanvirusinfectioncaseseriesandliteraturereviewfromasingleinstitution
AT singhalmayank powassanvirusinfectioncaseseriesandliteraturereviewfromasingleinstitution
AT guerrerodubert powassanvirusinfectioncaseseriesandliteraturereviewfromasingleinstitution
AT alontoaugusto powassanvirusinfectioncaseseriesandliteraturereviewfromasingleinstitution