Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease

Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease

Parkinson’s disease (PD) is one of the most common neurodegenerative disorders, and is caused by the death of dopamine neurons and neuroinflammation in the striatum and substantia nigra. Furthermore, the inflammatory response in PD is closely related to glial cell activation. This study examined the...

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Bibliographic Details
Main Authors: Seulah Lee, Yeon Ji Suh, Yujeong Lee, Seonguk Yang, Dong Geun Hong, Dinakaran Thirumalai, Seung-Cheol Chang, Ki Wung Chung, Young-Suk Jung, Hyung Ryong Moon, Hae Young Chung, Jaewon Lee
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antioxidants
Subjects:
Parkinson’s disease
neuroinflammation
MHY2699
barbiturate
MPTP
Online Access:https://www.mdpi.com/2076-3921/10/11/1855

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