Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report
Background: The management of anticoagulation for mechanical heart valves (MHVs) during pregnancy posed a special challenge. Mechanical thrombectomy (MT) was the standard treatment for acute ischemic stroke (AIS) in anterior circulation with large vessel occlusion. However, the efficacy and safety o...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023058243 |
| _version_ | 1797732980084441088 |
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| author | Renwei Zhang Li Peng Yao Xu Yumin Liu |
| author_facet | Renwei Zhang Li Peng Yao Xu Yumin Liu |
| author_sort | Renwei Zhang |
| collection | DOAJ |
| description | Background: The management of anticoagulation for mechanical heart valves (MHVs) during pregnancy posed a special challenge. Mechanical thrombectomy (MT) was the standard treatment for acute ischemic stroke (AIS) in anterior circulation with large vessel occlusion. However, the efficacy and safety of MT in the treatment of acute ischemic stroke in pregnancy were unknown. Case presentation: A 29-year-old woman with MHVs in her first pregnancy at 7 weeks’ gestation underwent MT because of a large occlusive thrombus in the end of the internal carotid artery despite therapeutic anticoagulation with low-molecular-weight heparin. This pregnant woman recovered well after MT with a modified rank score (mRS) of 0 at 90 days. Conclusion: At present, there was no standard protocol of anticoagulation therapy for pregnant women with MHVs. Acute ischemic stroke with large vessel occlusion in pregnancy was rare, but could bring devastating consequences for both mother and infant. Our case report demonstrated that MT could be safe and effective in pregnancy. |
| first_indexed | 2024-03-12T12:22:22Z |
| format | Article |
| id | doaj.art-24f9c050060b4cd9b1850749f760a9a0 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T12:22:22Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-24f9c050060b4cd9b1850749f760a9a02023-08-30T05:51:57ZengElsevierHeliyon2405-84402023-08-0198e18616Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case reportRenwei Zhang0Li Peng1Yao Xu2Yumin Liu3Department of Neurology, Zhongnan Hospital of Wuhan Universtiy, Wuhan, ChinaDepartment of Cardiology, Zhongnan Hospital of Wuhan Universtiy, Wuhan, ChinaDepartment of Neurology, Zhongnan Hospital of Wuhan Universtiy, Wuhan, ChinaDepartment of Neurology, Zhongnan Hospital of Wuhan Universtiy, Wuhan, China; Corresponding author.Background: The management of anticoagulation for mechanical heart valves (MHVs) during pregnancy posed a special challenge. Mechanical thrombectomy (MT) was the standard treatment for acute ischemic stroke (AIS) in anterior circulation with large vessel occlusion. However, the efficacy and safety of MT in the treatment of acute ischemic stroke in pregnancy were unknown. Case presentation: A 29-year-old woman with MHVs in her first pregnancy at 7 weeks’ gestation underwent MT because of a large occlusive thrombus in the end of the internal carotid artery despite therapeutic anticoagulation with low-molecular-weight heparin. This pregnant woman recovered well after MT with a modified rank score (mRS) of 0 at 90 days. Conclusion: At present, there was no standard protocol of anticoagulation therapy for pregnant women with MHVs. Acute ischemic stroke with large vessel occlusion in pregnancy was rare, but could bring devastating consequences for both mother and infant. Our case report demonstrated that MT could be safe and effective in pregnancy.http://www.sciencedirect.com/science/article/pii/S2405844023058243Mechanical heart valvesPregnant womanMechanical thrombectomyAcute ischemic strokeAnticoagulation |
| spellingShingle | Renwei Zhang Li Peng Yao Xu Yumin Liu Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report Heliyon Mechanical heart valves Pregnant woman Mechanical thrombectomy Acute ischemic stroke Anticoagulation |
| title | Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report |
| title_full | Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report |
| title_fullStr | Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report |
| title_full_unstemmed | Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report |
| title_short | Mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves： A case report |
| title_sort | mechanical thrombectomy for acute ischemic stroke with large vessel occlusion in pregnancy with mechanical heart valves a case report |
| topic | Mechanical heart valves Pregnant woman Mechanical thrombectomy Acute ischemic stroke Anticoagulation |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023058243 |
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