Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell

Sustained silencing peanut allergy by xanthopurpurin is associated with suppression of peripheral and bone marrow IgE-producing B cell

IntroductionPeanut allergy is an immunoglobulin E (IgE) mediated food allergy. Rubia cordifolia L. (R. cordifolia), a Chinese herbal medicine, protects against peanut-induced anaphylaxis by suppressing IgE production in vivo. This study aims to identify IgE-inhibitory compounds from the water extrac...

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Bibliographic Details
Main Authors: Nan Yang, Kamal Srivastava, Yujuan Chen, Hang Li, Anish Maskey, Patrick Yoo, Xiaohong Liu, Raj K. Tiwari, Jan Geliebter, Anna Nowak-Wegrzyn, Jixun Zhan, Xiu-Min Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Rubia cordifolia L.
food allergy
IgE
transcriptome
RNA-Seq
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1299484/full

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