ACE2 and TMPRSS2 distribution in the respiratory tract of different animal species and its correlation with SARS-CoV-2 tissue tropism

ACE2 and TMPRSS2 distribution in the respiratory tract of different animal species and its correlation with SARS-CoV-2 tissue tropism

ABSTRACTA wide range of animal species show variable susceptibility to SARS-CoV-2; however, host factors associated with varied susceptibility remain to be defined. Here, we examined whether susceptibility to SARS-CoV-2 and virus tropism in different animal species are dependent on the expression an...

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Main Authors: Mariano Carossino, Sudeh Izadmehr, Jessie D. Trujillo, Natasha N. Gaudreault, Wellesley Dittmar, Igor Morozov, Udeni B. R. Balasuriya, Carlos Cordon-Cardo, Adolfo García-Sastre, Juergen A. Richt
Format: Article
Language:English
Published: American Society for Microbiology 2024-02-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
domestic animal species
ACE2
TMPRSS2
viral pathogenesis
tropism
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03270-23

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