Systematic Profiling of Alternative mRNA Splicing Signature for Predicting Glioblastoma Prognosis

Emerging evidence suggests that alternative splicing (AS) is modified in cancer and is associated with cancer progression. Systematic analysis of AS signature in glioblastoma (GBM) is lacking and is greatly needed. We profiled genome-wide AS events in 498 GBM patients in TCGA using RNA-seq data, and...

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Bibliographic Details
Main Authors: Xueran Chen, Chenggang Zhao, Bing Guo, Zhiyang Zhao, Hongzhi Wang, Zhiyou Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00928/full

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