Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer

Novel 1,3,4-oxadiazole Targets STAT3 Signaling to Induce Antitumor Effect in Lung Cancer

Lung cancer is the leading type of malignancy in terms of occurrence and mortality in the global context. STAT3 is an oncogenic transcription factor that is persistently activated in many types of human malignancies, including lung cancer. In the present report, new oxadiazole conjugated indazoles w...

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Bibliographic Details
Main Authors: Vikas H. Malojirao, Swamy S. Girimanchanaika, Muthu K. Shanmugam, Ankith Sherapura, Dukanya, Prashant K. Metri, Vellingiri Vigneshwaran, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Shobith Rangappa, Chakrabhavi Dhananjaya Mohan, Basappa, Bettadathunga T. Prabhakar, Kanchugarakoppal S. Rangappa
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
lung cancer
antitumor
STAT3
apoptosis
Online Access:https://www.mdpi.com/2227-9059/8/9/368

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https://www.mdpi.com/2227-9059/8/9/368

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