Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows
Puerarin is an isoflavone extracted from <i>Pueraria mirifica</i>, a wildlife leguminous plant. It has been reported to possess antioxidant, anti-inflammatory, and anti-bacterial properties. However, the effects of directly adding puerarin to the diets of sows, in terms of reproductive p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/13/3/290 |
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| author | Shanchuan Cao Xinglai Li Heng Yin Juan Wang Jingbo Liu |
| author_facet | Shanchuan Cao Xinglai Li Heng Yin Juan Wang Jingbo Liu |
| author_sort | Shanchuan Cao |
| collection | DOAJ |
| description | Puerarin is an isoflavone extracted from <i>Pueraria mirifica</i>, a wildlife leguminous plant. It has been reported to possess antioxidant, anti-inflammatory, and anti-bacterial properties. However, the effects of directly adding puerarin to the diets of sows, in terms of reproductive performance and antioxidant properties, have not been reported. For this study, 240 sows with varying parities were selected and randomly divided into six treatment groups using a two × three experimental design. The six treatment groups consisted of two diets (control and puerarin) and three parities (zero, one, and two parities or more). The puerarin group was supplemented with 1 g/kg of puerarin. The experiment commenced with mating and continued until 21 days post-delivery. The sow reproductive performance was not affected by supplementing their diets with puerarin (<i>p</i> > 0.05). Dietary supplementation with puerarin significantly increased the daily body weight (BW) gain of piglets and their mean BW at weaning (<i>p</i> < 0.05). Compared with the control group, sows in the puerarin group had significantly higher glutathione peroxidase activity in serum and also significantly increased immunoglobulin A and G levels in serum, colostrum, and milk, but significantly lower malondialdehyde concentration in serum (<i>p</i> < 0.05). Thus, puerarin improved the immune response and antioxidant capacity of sows and increased the daily BW gain of their offspring. |
| first_indexed | 2024-04-24T18:36:23Z |
| format | Article |
| id | doaj.art-250b8945ebd0494faf5aaac044b26150 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-04-24T18:36:23Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-250b8945ebd0494faf5aaac044b261502024-03-27T13:18:28ZengMDPI AGAntioxidants2076-39212024-02-0113329010.3390/antiox13030290Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of SowsShanchuan Cao0Xinglai Li1Heng Yin2Juan Wang3Jingbo Liu4School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaSchool of Life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, ChinaPuerarin is an isoflavone extracted from <i>Pueraria mirifica</i>, a wildlife leguminous plant. It has been reported to possess antioxidant, anti-inflammatory, and anti-bacterial properties. However, the effects of directly adding puerarin to the diets of sows, in terms of reproductive performance and antioxidant properties, have not been reported. For this study, 240 sows with varying parities were selected and randomly divided into six treatment groups using a two × three experimental design. The six treatment groups consisted of two diets (control and puerarin) and three parities (zero, one, and two parities or more). The puerarin group was supplemented with 1 g/kg of puerarin. The experiment commenced with mating and continued until 21 days post-delivery. The sow reproductive performance was not affected by supplementing their diets with puerarin (<i>p</i> > 0.05). Dietary supplementation with puerarin significantly increased the daily body weight (BW) gain of piglets and their mean BW at weaning (<i>p</i> < 0.05). Compared with the control group, sows in the puerarin group had significantly higher glutathione peroxidase activity in serum and also significantly increased immunoglobulin A and G levels in serum, colostrum, and milk, but significantly lower malondialdehyde concentration in serum (<i>p</i> < 0.05). Thus, puerarin improved the immune response and antioxidant capacity of sows and increased the daily BW gain of their offspring.https://www.mdpi.com/2076-3921/13/3/290reproductive performancecolostrummilkcytokinesantioxidant parameterssow |
| spellingShingle | Shanchuan Cao Xinglai Li Heng Yin Juan Wang Jingbo Liu Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows Antioxidants reproductive performance colostrum milk cytokines antioxidant parameters sow |
| title | Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows |
| title_full | Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows |
| title_fullStr | Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows |
| title_full_unstemmed | Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows |
| title_short | Dietary Puerarin Supplementation Improves Immune Response and Antioxidant Capacity of Sows |
| title_sort | dietary puerarin supplementation improves immune response and antioxidant capacity of sows |
| topic | reproductive performance colostrum milk cytokines antioxidant parameters sow |
| url | https://www.mdpi.com/2076-3921/13/3/290 |
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