MiR-155 Regulates PAD4-Dependent Formation of Neutrophil Extracellular Traps

MiR-155 Regulates PAD4-Dependent Formation of Neutrophil Extracellular Traps

Accumulating data suggest that neutrophil extracellular traps (NETs) exert a key function in several diseases. Peptidylarginine deiminase 4 (PAD4) regulates NET formation via citrullination of histones. The aim of this study was to examine the role of miR-155 in controlling PAD4-dependent generation...

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Bibliographic Details
Main Authors: Avin Hawez, Amr Al-Haidari, Raed Madhi, Milladur Rahman, Henrik Thorlacius
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
microRNA
histone
inflammation
neutrophils
NETosis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02462/full

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