Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning
The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current competing models based on this premise. Commo...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-11-01
|
| Series: | Frontiers in Cell and Developmental Biology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fcell.2019.00257/full |
| _version_ | 1818577768426766336 |
|---|---|
| author | Antony J. Durston |
| author_facet | Antony J. Durston |
| author_sort | Antony J. Durston |
| collection | DOAJ |
| description | The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature. |
| first_indexed | 2024-12-16T06:35:10Z |
| format | Article |
| id | doaj.art-250e5ad7998d41d39f43e6494a700eac |
| institution | Directory Open Access Journal |
| issn | 2296-634X |
| language | English |
| last_indexed | 2024-12-16T06:35:10Z |
| publishDate | 2019-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cell and Developmental Biology |
| spelling | doaj.art-250e5ad7998d41d39f43e6494a700eac2022-12-21T22:40:48ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2019-11-01710.3389/fcell.2019.00257496093Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial PatterningAntony J. DurstonThe vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current competing models based on this premise. Common features and points of dissent are examined and a common model is distilled from what remains. This is an attempt to make sense of the literature.https://www.frontiersin.org/article/10.3389/fcell.2019.00257/fullHox genestime space translationaxial patterninggastrulationstem cellsHox-Hox interactions |
| spellingShingle | Antony J. Durston Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning Frontiers in Cell and Developmental Biology Hox genes time space translation axial patterning gastrulation stem cells Hox-Hox interactions |
| title | Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning |
| title_full | Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning |
| title_fullStr | Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning |
| title_full_unstemmed | Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning |
| title_short | Some Questions and Answers About the Role of Hox Temporal Collinearity in Vertebrate Axial Patterning |
| title_sort | some questions and answers about the role of hox temporal collinearity in vertebrate axial patterning |
| topic | Hox genes time space translation axial patterning gastrulation stem cells Hox-Hox interactions |
| url | https://www.frontiersin.org/article/10.3389/fcell.2019.00257/full |
| work_keys_str_mv | AT antonyjdurston somequestionsandanswersabouttheroleofhoxtemporalcollinearityinvertebrateaxialpatterning |