Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABAb autoreceptors in layer III of the entorhinal cortex

Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABAb autoreceptors in layer III of the entorhinal cortex

We studied the effect of kindling, a model of temporal lobe epilepsy, on the frequency-dependent information transfer from the entorhinal cortex to the hippocampus in vitro. In control rats repetitive synaptic activation of layer III projection cells resulted in a frequency dependent depression of t...

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Bibliographic Details
Main Authors: Tengis Gloveli, Joachim Behr, Tamar Dugladze, Zaal Kokaia, Merab Kokaia, Uwe Heinemann
Format: Article
Language:English
Published: Elsevier 2003-08-01
Series:Neurobiology of Disease
Subjects:
Projection cells
Intracellular recording
Kindling
GABAB
Synaptic transmission
In vitro
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000391

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