Proneural-mesenchymal antagonism dominates the patterns of phenotypic heterogeneity in glioblastoma
Summary: The aggressive nature of glioblastoma (GBM) – one of the deadliest forms of brain tumors – is majorly attributed to underlying phenotypic heterogeneity. Early attempts to classify this heterogeneity at a transcriptomic level in TCGA GBM cohort proposed the existence of four distinct molecul...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900422400405X |