Proneural-mesenchymal antagonism dominates the patterns of phenotypic heterogeneity in glioblastoma

Summary: The aggressive nature of glioblastoma (GBM) – one of the deadliest forms of brain tumors – is majorly attributed to underlying phenotypic heterogeneity. Early attempts to classify this heterogeneity at a transcriptomic level in TCGA GBM cohort proposed the existence of four distinct molecul...

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Bibliographic Details
Main Authors: Harshavardhan BV, Mohit Kumar Jolly
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400405X