Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis
We describe a new technique of platelet-rich plasma (PRP) infiltration for the treatment of severe knee osteoarthritis. PRP intra-articular infiltration is a promising treatment for knee osteoarthritis, but it still has some limitations in high-degree osteoarthritis. Diagnosis of osteoarthritis is b...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2014-12-01
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| Series: | Arthroscopy Techniques |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221262871400111X |
| _version_ | 1818664082373345280 |
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| author | Mikel Sánchez, M.D. Nicolás Fiz, M.D. Jorge Guadilla, M.D. Sabino Padilla, M.D., Ph.D. Eduardo Anitua, M.D., Ph.D. Pello Sánchez, M.Sc. Diego Delgado, Ph.D. |
| author_facet | Mikel Sánchez, M.D. Nicolás Fiz, M.D. Jorge Guadilla, M.D. Sabino Padilla, M.D., Ph.D. Eduardo Anitua, M.D., Ph.D. Pello Sánchez, M.Sc. Diego Delgado, Ph.D. |
| author_sort | Mikel Sánchez, M.D. |
| collection | DOAJ |
| description | We describe a new technique of platelet-rich plasma (PRP) infiltration for the treatment of severe knee osteoarthritis. PRP intra-articular infiltration is a promising treatment for knee osteoarthritis, but it still has some limitations in high-degree osteoarthritis. Diagnosis of osteoarthritis is based on clinical and radiographic findings, and patients with grade III or IV knee tibiofemoral osteoarthritis based on the Ahlbäck scale are considered candidates for this technique. The technique consists of performing intraosseous infiltration of PRP into the subchondral bone, which acts on this tissue and consequently on cartilage-bone communication. Although the intraosseous injection hinders the conventional knee intra-articular infiltration, it allows an extension of the range of action of the PRP, which acts directly on the subchondral bone, which is involved in the progression of osteoarthritis. Thus this technique involves a new administration of PRP that can delay knee arthroplasty; moreover, it can be applied for not only severe osteoarthritis but also other pathologies in which the subchondral bone is critical in the etiology, such as necrosis and osteochondral lesions. |
| first_indexed | 2024-12-17T05:27:05Z |
| format | Article |
| id | doaj.art-25115ce0573745f9a416f35d3efb3153 |
| institution | Directory Open Access Journal |
| issn | 2212-6287 |
| language | English |
| last_indexed | 2024-12-17T05:27:05Z |
| publishDate | 2014-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arthroscopy Techniques |
| spelling | doaj.art-25115ce0573745f9a416f35d3efb31532022-12-21T22:01:50ZengElsevierArthroscopy Techniques2212-62872014-12-0136e713e717Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee OsteoarthritisMikel Sánchez, M.D.0Nicolás Fiz, M.D.1Jorge Guadilla, M.D.2Sabino Padilla, M.D., Ph.D.3Eduardo Anitua, M.D., Ph.D.4Pello Sánchez, M.Sc.5Diego Delgado, Ph.D.6Arthroscopic Surgery Unit, Hospital Vithas San Jose, Vitoria-Gasteiz, SpainArthroscopic Surgery Unit, Hospital Vithas San Jose, Vitoria-Gasteiz, Spain; Biotechnology Institute, Vitoria-Gasteiz, SpainArthroscopic Surgery Unit, Hospital Vithas San Jose, Vitoria-Gasteiz, SpainBiotechnology Institute, Vitoria-Gasteiz, Spain; Foundation Eduardo Anitua, Vitoria-Gasteiz, SpainBiotechnology Institute, Vitoria-Gasteiz, Spain; Foundation Eduardo Anitua, Vitoria-Gasteiz, SpainArthroscopic Surgery Unit Research, Hospital Vithas San Jose, Vitoria-Gasteiz, SpainArthroscopic Surgery Unit Research, Hospital Vithas San Jose, Vitoria-Gasteiz, Spain; Address correspondence to Diego Delgado, Ph.D., Arthroscopic Surgery Unit Research, Hospital Vithas San Jose, Calle del Beato Tomás de Zumárraga 10, 01008 Vitoria-Gasteiz, Spain.We describe a new technique of platelet-rich plasma (PRP) infiltration for the treatment of severe knee osteoarthritis. PRP intra-articular infiltration is a promising treatment for knee osteoarthritis, but it still has some limitations in high-degree osteoarthritis. Diagnosis of osteoarthritis is based on clinical and radiographic findings, and patients with grade III or IV knee tibiofemoral osteoarthritis based on the Ahlbäck scale are considered candidates for this technique. The technique consists of performing intraosseous infiltration of PRP into the subchondral bone, which acts on this tissue and consequently on cartilage-bone communication. Although the intraosseous injection hinders the conventional knee intra-articular infiltration, it allows an extension of the range of action of the PRP, which acts directly on the subchondral bone, which is involved in the progression of osteoarthritis. Thus this technique involves a new administration of PRP that can delay knee arthroplasty; moreover, it can be applied for not only severe osteoarthritis but also other pathologies in which the subchondral bone is critical in the etiology, such as necrosis and osteochondral lesions.http://www.sciencedirect.com/science/article/pii/S221262871400111X |
| spellingShingle | Mikel Sánchez, M.D. Nicolás Fiz, M.D. Jorge Guadilla, M.D. Sabino Padilla, M.D., Ph.D. Eduardo Anitua, M.D., Ph.D. Pello Sánchez, M.Sc. Diego Delgado, Ph.D. Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis Arthroscopy Techniques |
| title | Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis |
| title_full | Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis |
| title_fullStr | Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis |
| title_full_unstemmed | Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis |
| title_short | Intraosseous Infiltration of Platelet-Rich Plasma for Severe Knee Osteoarthritis |
| title_sort | intraosseous infiltration of platelet rich plasma for severe knee osteoarthritis |
| url | http://www.sciencedirect.com/science/article/pii/S221262871400111X |
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