Physiological Changes of the Thyroid Gland Function in Pregnancy

The literature data regarding changes in thyroid function during pregnancy were analyzed. There has been described a number of factors (increased levels of human chorionic gonadotropin, estrogen, changes in deiodination processese, the need for iodine, etc.) influencing the synthesis of free and bou...

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Main Authors: O.S. Prylutskyi, S.Yu. Hlushych
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2015-08-01
Series:Mìžnarodnij Endokrinologìčnij Žurnal
Subjects:
Online Access:http://iej.zaslavsky.com.ua/article/view/75202
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author O.S. Prylutskyi
S.Yu. Hlushych
author_facet O.S. Prylutskyi
S.Yu. Hlushych
author_sort O.S. Prylutskyi
collection DOAJ
description The literature data regarding changes in thyroid function during pregnancy were analyzed. There has been described a number of factors (increased levels of human chorionic gonadotropin, estrogen, changes in deiodination processese, the need for iodine, etc.) influencing the synthesis of free and bound fractions of thyroid hormones. Characteristic differences of the above data in different trimesters of pregnancy are presented. It is shown that some pregnant women may have thyroid hormone levels beyond the normal range. According to the literature, in 9.7–30 % of women, thyroid-stimulating hormone level does not meet the trimester-specific intervals. The intense functioning of the thyroid gland in the mother increases the risk of pathological changes in it, and a violation of its functions is the risk of thyroid disease in the fetus too. In view of the above, timely diagnosis of thyroid function, control of the activity of adaptive processes in the pituitary-thyroid system in pregnant women are important.
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spelling doaj.art-25142a5647a1469fb5cb2bd0f13038d32022-12-21T17:23:53ZengZaslavsky O.Yu.Mìžnarodnij Endokrinologìčnij Žurnal2224-07212307-14272015-08-01115.6914014610.22141/2224-0721.5.69.2015.7520275202Physiological Changes of the Thyroid Gland Function in PregnancyO.S. Prylutskyi0S.Yu. Hlushych1Donetsk National Medical University named after M. Horkyi, Krasnyi Liman, UkraineDonetsk National Medical University named after M. Horkyi, Krasnyi Liman, UkraineThe literature data regarding changes in thyroid function during pregnancy were analyzed. There has been described a number of factors (increased levels of human chorionic gonadotropin, estrogen, changes in deiodination processese, the need for iodine, etc.) influencing the synthesis of free and bound fractions of thyroid hormones. Characteristic differences of the above data in different trimesters of pregnancy are presented. It is shown that some pregnant women may have thyroid hormone levels beyond the normal range. According to the literature, in 9.7–30 % of women, thyroid-stimulating hormone level does not meet the trimester-specific intervals. The intense functioning of the thyroid gland in the mother increases the risk of pathological changes in it, and a violation of its functions is the risk of thyroid disease in the fetus too. In view of the above, timely diagnosis of thyroid function, control of the activity of adaptive processes in the pituitary-thyroid system in pregnant women are important.http://iej.zaslavsky.com.ua/article/view/75202thyroid glandhormonespregnancy
spellingShingle O.S. Prylutskyi
S.Yu. Hlushych
Physiological Changes of the Thyroid Gland Function in Pregnancy
Mìžnarodnij Endokrinologìčnij Žurnal
thyroid gland
hormones
pregnancy
title Physiological Changes of the Thyroid Gland Function in Pregnancy
title_full Physiological Changes of the Thyroid Gland Function in Pregnancy
title_fullStr Physiological Changes of the Thyroid Gland Function in Pregnancy
title_full_unstemmed Physiological Changes of the Thyroid Gland Function in Pregnancy
title_short Physiological Changes of the Thyroid Gland Function in Pregnancy
title_sort physiological changes of the thyroid gland function in pregnancy
topic thyroid gland
hormones
pregnancy
url http://iej.zaslavsky.com.ua/article/view/75202
work_keys_str_mv AT osprylutskyi physiologicalchangesofthethyroidglandfunctioninpregnancy
AT syuhlushych physiologicalchangesofthethyroidglandfunctioninpregnancy