p21 as a Predictor and Prognostic Indicator of Clinical Outcome in Rectal Cancer Patients

p21 as a Predictor and Prognostic Indicator of Clinical Outcome in Rectal Cancer Patients

The cell cycle plays a key and complex role in the development of human cancers. p21 is a potent cyclin-dependent kinase inhibitor (CDKI) involved in the promotion of cell cycle arrest and the regulation of cellular senescence. Altered p21 expression in rectal cancer cells may affect tumor cells’ be...

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Bibliographic Details
Main Authors: Li Ching Ooi, Vincent Ho, Jing Zhou Zhu, Stephanie Lim, Liping Chung, Askar Abubakar, Tristan Rutland, Wei Chua, Weng Ng, Mark Lee, Matthew Morgan, Scott MacKenzie, Cheok Soon Lee
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
p21
rectal cancer (CRC)
tissue microarrays
radiotherapy
Online Access:https://www.mdpi.com/1422-0067/25/2/725

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