Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics Analysis

Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics Analysis

Background: Intervertebral disc degeneration (IDD), characterized by diverse pathological changes, causes low back pain (LBP). However, prophylactic and delaying treatments for IDD are limited. The aim of our study was to investigate the gene network and biomarkers of IDD and suggest potential thera...

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Bibliographic Details
Main Authors: Jianjun Li, Cheng Yu, Songjia Ni, Yang Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
intervertebral disc degeneration
differentially expressed genes
hub genes
integrated bioinformatics
protein–protein interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.864100/full

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