Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1
Objective: Cardiovascular disease is the leading cause of death in patients with bipolar disorder. The aim of this study was to evaluate the factors associated with positive coronary calcium score (CCS) in individuals with bipolar disorder type 1. Methods: Patients from the Bipolar Disorder Program...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Associação Brasileira de Psiquiatria (ABP)
2017-10-01
|
| Series: | Brazilian Journal of Psychiatry |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462017005017105&lng=en&tlng=en |
| _version_ | 1818136386382856192 |
|---|---|
| author | Aline R. Wageck Felipe S. Torres Clarissa S. Gama Dayane S. Martins Ellen Scotton Ramiro Reckziegel Monise Costanzi Regis G. Rosa Flávio Kapczinski Maurício Kunz |
| author_facet | Aline R. Wageck Felipe S. Torres Clarissa S. Gama Dayane S. Martins Ellen Scotton Ramiro Reckziegel Monise Costanzi Regis G. Rosa Flávio Kapczinski Maurício Kunz |
| author_sort | Aline R. Wageck |
| collection | DOAJ |
| description | Objective: Cardiovascular disease is the leading cause of death in patients with bipolar disorder. The aim of this study was to evaluate the factors associated with positive coronary calcium score (CCS) in individuals with bipolar disorder type 1. Methods: Patients from the Bipolar Disorder Program at Hospital de Clínicas de Porto Alegre, Brazil, underwent computed tomography scanning for calcium score measurement. Clinical and sociodemographic variables were compared between patients according to their CCS status: negative (CCS = 0) or positive (CCS > 0). Poisson regression analysis was used to examine the association of CCS with number of psychiatric hospitalizations. Results: Out of 41 patients evaluated, only 10 had a positive CCS. Individuals in the CCS-positive group were older (55.2±4.2 vs. 43.1±10.0 years; p = 0.001) and had more psychiatric hospitalizations (4.7±3.0 vs. 2.6±2.5; p = 0.04) when compared with CCS- negative subjects. The number of previous psychiatric hospitalizations correlated positively with CCS (p < 0.001). Conclusion: Age and number of psychiatric hospitalizations were significantly associated with higher CCS, which might be a potential method for diagnosis and stratification of cardiovascular disease in bipolar patients. There is a need for increased awareness of risk assessment in this population. |
| first_indexed | 2024-12-11T09:39:35Z |
| format | Article |
| id | doaj.art-252c83ea157640529d6dc2f8af6cb503 |
| institution | Directory Open Access Journal |
| issn | 1809-452X |
| language | English |
| last_indexed | 2024-12-11T09:39:35Z |
| publishDate | 2017-10-01 |
| publisher | Associação Brasileira de Psiquiatria (ABP) |
| record_format | Article |
| series | Brazilian Journal of Psychiatry |
| spelling | doaj.art-252c83ea157640529d6dc2f8af6cb5032022-12-22T01:12:43ZengAssociação Brasileira de Psiquiatria (ABP)Brazilian Journal of Psychiatry1809-452X2017-10-01010.1590/1516-4446-2017-2253S1516-44462017005017105Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1Aline R. WageckFelipe S. TorresClarissa S. GamaDayane S. MartinsEllen ScottonRamiro ReckziegelMonise CostanziRegis G. RosaFlávio KapczinskiMaurício KunzObjective: Cardiovascular disease is the leading cause of death in patients with bipolar disorder. The aim of this study was to evaluate the factors associated with positive coronary calcium score (CCS) in individuals with bipolar disorder type 1. Methods: Patients from the Bipolar Disorder Program at Hospital de Clínicas de Porto Alegre, Brazil, underwent computed tomography scanning for calcium score measurement. Clinical and sociodemographic variables were compared between patients according to their CCS status: negative (CCS = 0) or positive (CCS > 0). Poisson regression analysis was used to examine the association of CCS with number of psychiatric hospitalizations. Results: Out of 41 patients evaluated, only 10 had a positive CCS. Individuals in the CCS-positive group were older (55.2±4.2 vs. 43.1±10.0 years; p = 0.001) and had more psychiatric hospitalizations (4.7±3.0 vs. 2.6±2.5; p = 0.04) when compared with CCS- negative subjects. The number of previous psychiatric hospitalizations correlated positively with CCS (p < 0.001). Conclusion: Age and number of psychiatric hospitalizations were significantly associated with higher CCS, which might be a potential method for diagnosis and stratification of cardiovascular disease in bipolar patients. There is a need for increased awareness of risk assessment in this population.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462017005017105&lng=en&tlng=enBipolar disordercardiovascular diseasesdiagnostic techniquescardiovascularcoronary disease |
| spellingShingle | Aline R. Wageck Felipe S. Torres Clarissa S. Gama Dayane S. Martins Ellen Scotton Ramiro Reckziegel Monise Costanzi Regis G. Rosa Flávio Kapczinski Maurício Kunz Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 Brazilian Journal of Psychiatry Bipolar disorder cardiovascular diseases diagnostic techniques cardiovascular coronary disease |
| title | Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| title_full | Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| title_fullStr | Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| title_full_unstemmed | Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| title_short | Cardiovascular risk and bipolar disorder: factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| title_sort | cardiovascular risk and bipolar disorder factors associated with a positive coronary calcium score in patients with bipolar disorder type 1 |
| topic | Bipolar disorder cardiovascular diseases diagnostic techniques cardiovascular coronary disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462017005017105&lng=en&tlng=en |
| work_keys_str_mv | AT alinerwageck cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT felipestorres cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT clarissasgama cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT dayanesmartins cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT ellenscotton cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT ramiroreckziegel cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT monisecostanzi cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT regisgrosa cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT flaviokapczinski cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 AT mauriciokunz cardiovascularriskandbipolardisorderfactorsassociatedwithapositivecoronarycalciumscoreinpatientswithbipolardisordertype1 |