Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge

Pseudotumoral hepatic tuberculosis (TB) is an exceptionally rare manifestation of TB, often mimicking hepatic malignancy on imaging studies. We report the case of a 51-year-old female diagnosed with a low-grade tubulovillous adenoma of the ampulla of Vater, who presented with hepatic lesions initial...

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Main Authors: Mohamed Labied, Rahma Khabab, Chorouk Mountassir, Ghizlane Lembarki, Mouna Sabiri, Samira Lezar
Format: Article
Language:English
Published: SMC MEDIA SRL 2025-02-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/5162
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author Mohamed Labied
Rahma Khabab
Chorouk Mountassir
Ghizlane Lembarki
Mouna Sabiri
Samira Lezar
author_facet Mohamed Labied
Rahma Khabab
Chorouk Mountassir
Ghizlane Lembarki
Mouna Sabiri
Samira Lezar
author_sort Mohamed Labied
collection DOAJ
description Pseudotumoral hepatic tuberculosis (TB) is an exceptionally rare manifestation of TB, often mimicking hepatic malignancy on imaging studies. We report the case of a 51-year-old female diagnosed with a low-grade tubulovillous adenoma of the ampulla of Vater, who presented with hepatic lesions initially suspected to be metastatic. Magnetic resonance imaging (MRI) revealed multiple hypointense lesions with heterogeneous enhancement and restricted diffusion. Histopathological examination of a liver biopsy confirmed the diagnosis of pseudotumoral TB. The patient underwent a 6-month course of antitubercular therapy, after which follow-up MRI demonstrated complete resolution of the hepatic lesions. This case highlights the importance of considering pseudotumoral hepatic TB in the differential diagnosis of hepatic masses, particularly in regions with a high prevalence of TB. Histological confirmation remains essential, and timely initiation of antitubercular treatment can result in excellent clinical outcomes.
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spelling doaj.art-252cee0f96f44195b6c74850a67e5d2d2025-03-03T14:59:44ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942025-02-0110.12890/2025_0051624697Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challengeMohamed Labied0Rahma Khabab1Chorouk Mountassir2Ghizlane Lembarki3Mouna Sabiri4Samira Lezar5Ibn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoIbn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoIbn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoIbn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoIbn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoIbn Rochd University Hospital, Faculty of Medicine and Pharmacy of Casablanca, Casablanca, MoroccoPseudotumoral hepatic tuberculosis (TB) is an exceptionally rare manifestation of TB, often mimicking hepatic malignancy on imaging studies. We report the case of a 51-year-old female diagnosed with a low-grade tubulovillous adenoma of the ampulla of Vater, who presented with hepatic lesions initially suspected to be metastatic. Magnetic resonance imaging (MRI) revealed multiple hypointense lesions with heterogeneous enhancement and restricted diffusion. Histopathological examination of a liver biopsy confirmed the diagnosis of pseudotumoral TB. The patient underwent a 6-month course of antitubercular therapy, after which follow-up MRI demonstrated complete resolution of the hepatic lesions. This case highlights the importance of considering pseudotumoral hepatic TB in the differential diagnosis of hepatic masses, particularly in regions with a high prevalence of TB. Histological confirmation remains essential, and timely initiation of antitubercular treatment can result in excellent clinical outcomes.https://www.ejcrim.com/index.php/EJCRIM/article/view/5162livermrituberculosispseudotumor
spellingShingle Mohamed Labied
Rahma Khabab
Chorouk Mountassir
Ghizlane Lembarki
Mouna Sabiri
Samira Lezar
Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
European Journal of Case Reports in Internal Medicine
liver
mri
tuberculosis
pseudotumor
title Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
title_full Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
title_fullStr Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
title_full_unstemmed Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
title_short Rare pseudotumoral hepatic tuberculosis mimicking malignancy: a diagnostic and therapeutic challenge
title_sort rare pseudotumoral hepatic tuberculosis mimicking malignancy a diagnostic and therapeutic challenge
topic liver
mri
tuberculosis
pseudotumor
url https://www.ejcrim.com/index.php/EJCRIM/article/view/5162
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