Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems
Mitochondria are known as the powerhouse of eukaryotic cells. Energy production occurs in specific dynamic membrane invaginations in the inner mitochondrial membrane called cristae. Although the integrity of these structures is recognized as a key point for proper mitochondrial function, less is kno...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Membranes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0375/11/7/465 |
| _version_ | 1827688912232906752 |
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| author | Frédéric Joubert Nicolas Puff |
| author_facet | Frédéric Joubert Nicolas Puff |
| author_sort | Frédéric Joubert |
| collection | DOAJ |
| description | Mitochondria are known as the powerhouse of eukaryotic cells. Energy production occurs in specific dynamic membrane invaginations in the inner mitochondrial membrane called cristae. Although the integrity of these structures is recognized as a key point for proper mitochondrial function, less is known about the mechanisms at the origin of their plasticity and organization, and how they can influence mitochondria function. Here, we review the studies which question the role of lipid membrane composition based mainly on minimal model systems. |
| first_indexed | 2024-03-10T10:07:16Z |
| format | Article |
| id | doaj.art-252df7d18d464c2ca2e560fe631ed4da |
| institution | Directory Open Access Journal |
| issn | 2077-0375 |
| language | English |
| last_indexed | 2024-03-10T10:07:16Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Membranes |
| spelling | doaj.art-252df7d18d464c2ca2e560fe631ed4da2023-11-22T01:25:11ZengMDPI AGMembranes2077-03752021-06-0111746510.3390/membranes11070465Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model SystemsFrédéric Joubert0Nicolas Puff1Laboratoire Jean Perrin, CNRS, Sorbonne Université, UMR 8237, 75005 Paris, FranceFaculté des Sciences et Ingénierie, Sorbonne Université, UFR 925 Physique, 75005 Paris, FranceMitochondria are known as the powerhouse of eukaryotic cells. Energy production occurs in specific dynamic membrane invaginations in the inner mitochondrial membrane called cristae. Although the integrity of these structures is recognized as a key point for proper mitochondrial function, less is known about the mechanisms at the origin of their plasticity and organization, and how they can influence mitochondria function. Here, we review the studies which question the role of lipid membrane composition based mainly on minimal model systems.https://www.mdpi.com/2077-0375/11/7/465cardiolipinmitochondriacristaecurvature-based sortingcone-shaped lipid asymmetrynonbilayer structures |
| spellingShingle | Frédéric Joubert Nicolas Puff Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems Membranes cardiolipin mitochondria cristae curvature-based sorting cone-shaped lipid asymmetry nonbilayer structures |
| title | Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems |
| title_full | Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems |
| title_fullStr | Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems |
| title_full_unstemmed | Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems |
| title_short | Mitochondrial Cristae Architecture and Functions: Lessons from Minimal Model Systems |
| title_sort | mitochondrial cristae architecture and functions lessons from minimal model systems |
| topic | cardiolipin mitochondria cristae curvature-based sorting cone-shaped lipid asymmetry nonbilayer structures |
| url | https://www.mdpi.com/2077-0375/11/7/465 |
| work_keys_str_mv | AT fredericjoubert mitochondrialcristaearchitectureandfunctionslessonsfromminimalmodelsystems AT nicolaspuff mitochondrialcristaearchitectureandfunctionslessonsfromminimalmodelsystems |