Trimetazidine Alleviates Postresuscitation Myocardial Dysfunction and Improves 96‐Hour Survival in a Ventricular Fibrillation Rat Model

Trimetazidine Alleviates Postresuscitation Myocardial Dysfunction and Improves 96‐Hour Survival in a Ventricular Fibrillation Rat Model

Background Myocardial dysfunction is a critical cause of post‐cardiac arrest hemodynamic instability and circulatory failure that may lead to early mortality after resuscitation. Trimetazidine is a metabolic agent that has been demonstrated to provide protective effects in myocardial ischemia. Howev...

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Bibliographic Details
Main Authors: Jingru Li, Yuantong Qi, Jianjie Wang, Chenxi Dai, Bihua Chen, Yongqin Li
Format: Article
Language:English
Published: Wiley 2022-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac arrest
cardiopulmonary resuscitation
myocardial dysfunction
oxidative stress
targeted temperature management
trimetazidine
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.121.023378

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.121.023378

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