Cannabis Pharmacogenomics: A Path to Personalized Medicine
Cannabis and related compounds have created significant research interest as a promising therapy in many disorders. However, the individual therapeutic effects of cannabinoids and the incidence of side effects are still difficult to determine. Pharmacogenomics may provide the answers to many questio...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-04-01
|
| Series: | Current Issues in Molecular Biology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1467-3045/45/4/228 |
| _version_ | 1797605909646540800 |
|---|---|
| author | Mariana Babayeva Zvi G. Loewy |
| author_facet | Mariana Babayeva Zvi G. Loewy |
| author_sort | Mariana Babayeva |
| collection | DOAJ |
| description | Cannabis and related compounds have created significant research interest as a promising therapy in many disorders. However, the individual therapeutic effects of cannabinoids and the incidence of side effects are still difficult to determine. Pharmacogenomics may provide the answers to many questions and concerns regarding the cannabis/cannabinoid treatment and help us to understand the variability in individual responses and associated risks. Pharmacogenomics research has made meaningful progress in identifying genetic variations that play a critical role in interpatient variability in response to cannabis. This review classifies the current knowledge of pharmacogenomics associated with medical marijuana and related compounds and can assist in improving the outcomes of cannabinoid therapy and to minimize the adverse effects of cannabis use. Specific examples of pharmacogenomics informing pharmacotherapy as a path to personalized medicine are discussed. |
| first_indexed | 2024-03-11T05:07:46Z |
| format | Article |
| id | doaj.art-25337d6f47e1408381edfd1726e0fade |
| institution | Directory Open Access Journal |
| issn | 1467-3037 1467-3045 |
| language | English |
| last_indexed | 2024-03-11T05:07:46Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Issues in Molecular Biology |
| spelling | doaj.art-25337d6f47e1408381edfd1726e0fade2023-11-17T18:48:04ZengMDPI AGCurrent Issues in Molecular Biology1467-30371467-30452023-04-014543479351410.3390/cimb45040228Cannabis Pharmacogenomics: A Path to Personalized MedicineMariana Babayeva0Zvi G. Loewy1Department of Biomedical and Pharmaceutical Sciences, Touro College of Pharmacy, New York, NY 10027, USADepartment of Biomedical and Pharmaceutical Sciences, Touro College of Pharmacy, New York, NY 10027, USACannabis and related compounds have created significant research interest as a promising therapy in many disorders. However, the individual therapeutic effects of cannabinoids and the incidence of side effects are still difficult to determine. Pharmacogenomics may provide the answers to many questions and concerns regarding the cannabis/cannabinoid treatment and help us to understand the variability in individual responses and associated risks. Pharmacogenomics research has made meaningful progress in identifying genetic variations that play a critical role in interpatient variability in response to cannabis. This review classifies the current knowledge of pharmacogenomics associated with medical marijuana and related compounds and can assist in improving the outcomes of cannabinoid therapy and to minimize the adverse effects of cannabis use. Specific examples of pharmacogenomics informing pharmacotherapy as a path to personalized medicine are discussed.https://www.mdpi.com/1467-3045/45/4/228pharmacogenomicscannabiscannabinoidspersonalized medicine |
| spellingShingle | Mariana Babayeva Zvi G. Loewy Cannabis Pharmacogenomics: A Path to Personalized Medicine Current Issues in Molecular Biology pharmacogenomics cannabis cannabinoids personalized medicine |
| title | Cannabis Pharmacogenomics: A Path to Personalized Medicine |
| title_full | Cannabis Pharmacogenomics: A Path to Personalized Medicine |
| title_fullStr | Cannabis Pharmacogenomics: A Path to Personalized Medicine |
| title_full_unstemmed | Cannabis Pharmacogenomics: A Path to Personalized Medicine |
| title_short | Cannabis Pharmacogenomics: A Path to Personalized Medicine |
| title_sort | cannabis pharmacogenomics a path to personalized medicine |
| topic | pharmacogenomics cannabis cannabinoids personalized medicine |
| url | https://www.mdpi.com/1467-3045/45/4/228 |
| work_keys_str_mv | AT marianababayeva cannabispharmacogenomicsapathtopersonalizedmedicine AT zvigloewy cannabispharmacogenomicsapathtopersonalizedmedicine |