Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration

In this review, we present the current trends in photonic biosensors, focusing on devices based on lab-on-a-chip (LOC) systems capable of simultaneously detecting multiple real-life diseases on a single platform. The first section lists the advantages and challenges of building LOC platforms based o...

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Main Authors: Jhonattan C. Ramirez, Daniel Grajales García, Jesús Maldonado, Adrián Fernández-Gavela
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/10/10/398
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author Jhonattan C. Ramirez
Daniel Grajales García
Jesús Maldonado
Adrián Fernández-Gavela
author_facet Jhonattan C. Ramirez
Daniel Grajales García
Jesús Maldonado
Adrián Fernández-Gavela
author_sort Jhonattan C. Ramirez
collection DOAJ
description In this review, we present the current trends in photonic biosensors, focusing on devices based on lab-on-a-chip (LOC) systems capable of simultaneously detecting multiple real-life diseases on a single platform. The first section lists the advantages and challenges of building LOC platforms based on integrated optics. Some of the most popular materials for the fabrication of microfluidic cells are also shown. Then, a review of the latest developments in biosensors using the evanescent wave detection principle is provided; this includes interferometric biosensors, ring resonators, and photonic crystals, including a brief description of commercial solutions, if available. Then, a review of the latest advances in surface plasmon resonance (SPR) biosensors is presented, including localized-SPRs (LSPRs). A brief comparison between the benefits and required improvements on each kind of biosensor is discussed at the end of each section. Finally, prospects in the field of LOC biosensors based on integrated optics are glimpsed.
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spelling doaj.art-2536ed7aadee4fd3b7ea6bf97af2fd412023-11-23T23:30:02ZengMDPI AGChemosensors2227-90402022-09-01101039810.3390/chemosensors10100398Current Trends in Photonic Biosensors: Advances towards Multiplexed IntegrationJhonattan C. Ramirez0Daniel Grajales García1Jesús Maldonado2Adrián Fernández-Gavela3Departamento de Engenharia Eletrônica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte 31270-901, BrazilSchool of Engineering and Sciences, Tecnológico de Monterrey, Monterrey 64849, MexicoDepartment of Neurosurgery, School of Medicine, Yale University, New Haven, CT 06510, USAPhysics Department, University of Oviedo, 33007 Oviedo, SpainIn this review, we present the current trends in photonic biosensors, focusing on devices based on lab-on-a-chip (LOC) systems capable of simultaneously detecting multiple real-life diseases on a single platform. The first section lists the advantages and challenges of building LOC platforms based on integrated optics. Some of the most popular materials for the fabrication of microfluidic cells are also shown. Then, a review of the latest developments in biosensors using the evanescent wave detection principle is provided; this includes interferometric biosensors, ring resonators, and photonic crystals, including a brief description of commercial solutions, if available. Then, a review of the latest advances in surface plasmon resonance (SPR) biosensors is presented, including localized-SPRs (LSPRs). A brief comparison between the benefits and required improvements on each kind of biosensor is discussed at the end of each section. Finally, prospects in the field of LOC biosensors based on integrated optics are glimpsed.https://www.mdpi.com/2227-9040/10/10/398photonic biosensormultiplexed detectionLOCreal-life applicationssolutions
spellingShingle Jhonattan C. Ramirez
Daniel Grajales García
Jesús Maldonado
Adrián Fernández-Gavela
Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
Chemosensors
photonic biosensor
multiplexed detection
LOC
real-life applications
solutions
title Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
title_full Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
title_fullStr Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
title_full_unstemmed Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
title_short Current Trends in Photonic Biosensors: Advances towards Multiplexed Integration
title_sort current trends in photonic biosensors advances towards multiplexed integration
topic photonic biosensor
multiplexed detection
LOC
real-life applications
solutions
url https://www.mdpi.com/2227-9040/10/10/398
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AT jesusmaldonado currenttrendsinphotonicbiosensorsadvancestowardsmultiplexedintegration
AT adrianfernandezgavela currenttrendsinphotonicbiosensorsadvancestowardsmultiplexedintegration