Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia
Common variable immunodeficiency (CVID) is a rare disorder characterized by primary antibody deficiency leading to hypogammaglobulinemia and increased risk of infections. Pulmonary hypertension (PH) is an unusual complication of CVID and may be associated with chronic hypoxemic respiratory failure....
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SEEd
2023-01-01
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| Series: | Clinical Management Issues |
| Subjects: | |
| Online Access: | http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1521 |
| _version_ | 1797938447898378240 |
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| author | Paolo Ghiringhelli Fabrizio Foieni Girolamo Sala Alessandro Diana Beatrice Valvo Mariella Ciola Michele Zaza Roberto Bertolini Cinzia Simoni Lorenzo Bellintani Andrea Agostinelli Federica Macchi Sara Limbiati Michela Provisione |
| author_facet | Paolo Ghiringhelli Fabrizio Foieni Girolamo Sala Alessandro Diana Beatrice Valvo Mariella Ciola Michele Zaza Roberto Bertolini Cinzia Simoni Lorenzo Bellintani Andrea Agostinelli Federica Macchi Sara Limbiati Michela Provisione |
| author_sort | Paolo Ghiringhelli |
| collection | DOAJ |
| description | Common variable immunodeficiency (CVID) is a rare disorder characterized by primary antibody deficiency leading to hypogammaglobulinemia and increased risk of infections. Pulmonary hypertension (PH) is an unusual complication of CVID and may be associated with chronic hypoxemic respiratory failure.
We described the case of a 47-year-old female patient hospitalized with worsening dyspnea, which had emerged about 10 days before and was associated with productive cough. 26 years before, she was diagnosed with common variable hypogammaglobulinemia, that was treated with intravenous immunoglobulin infusions for at least 20 years. She had suffered from recurrent secondary infections of the respiratory tract with inveterate bronchiectasis, pulmonary hypertension, and chronic respiratory failure.
This case suggests that Internal Medicine wards, due to their global vision of the patient, are well suited to manage subjects with serious, complex, and genetically determined pathologies. |
| first_indexed | 2024-04-10T19:00:54Z |
| format | Article |
| id | doaj.art-253b16f7d1b9431e9056bb9bec484ca2 |
| institution | Directory Open Access Journal |
| issn | 2283-3137 |
| language | English |
| last_indexed | 2024-04-10T19:00:54Z |
| publishDate | 2023-01-01 |
| publisher | SEEd |
| record_format | Article |
| series | Clinical Management Issues |
| spelling | doaj.art-253b16f7d1b9431e9056bb9bec484ca22023-01-31T09:42:02ZengSEEdClinical Management Issues2283-31372023-01-0117110.7175/cmi.v17i1.15211354Pulmonary Complications in a Patient with Common Variable HypogammaglobulinemiaPaolo Ghiringhelli0Fabrizio Foieni1Girolamo Sala2Alessandro Diana3Beatrice Valvo4Mariella Ciola5Michele Zaza6Roberto Bertolini7Cinzia Simoni8Lorenzo Bellintani9Andrea Agostinelli10Federica Macchi11Sara Limbiati12Michela Provisione13ASST Valle Olona, Presidio Ospedaliero di Saronno, UOC Medicina Interna, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Gallarate, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Gallarate, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyMedicina Interna, Ospedale di Circolo di Busto Arsizio, ASST Valle Olona, ItalyCommon variable immunodeficiency (CVID) is a rare disorder characterized by primary antibody deficiency leading to hypogammaglobulinemia and increased risk of infections. Pulmonary hypertension (PH) is an unusual complication of CVID and may be associated with chronic hypoxemic respiratory failure. We described the case of a 47-year-old female patient hospitalized with worsening dyspnea, which had emerged about 10 days before and was associated with productive cough. 26 years before, she was diagnosed with common variable hypogammaglobulinemia, that was treated with intravenous immunoglobulin infusions for at least 20 years. She had suffered from recurrent secondary infections of the respiratory tract with inveterate bronchiectasis, pulmonary hypertension, and chronic respiratory failure. This case suggests that Internal Medicine wards, due to their global vision of the patient, are well suited to manage subjects with serious, complex, and genetically determined pathologies.http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1521common variable hypogammaglobulinemia, respiratory failure, pulmonary hypertension |
| spellingShingle | Paolo Ghiringhelli Fabrizio Foieni Girolamo Sala Alessandro Diana Beatrice Valvo Mariella Ciola Michele Zaza Roberto Bertolini Cinzia Simoni Lorenzo Bellintani Andrea Agostinelli Federica Macchi Sara Limbiati Michela Provisione Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia Clinical Management Issues common variable hypogammaglobulinemia, respiratory failure, pulmonary hypertension |
| title | Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia |
| title_full | Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia |
| title_fullStr | Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia |
| title_full_unstemmed | Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia |
| title_short | Pulmonary Complications in a Patient with Common Variable Hypogammaglobulinemia |
| title_sort | pulmonary complications in a patient with common variable hypogammaglobulinemia |
| topic | common variable hypogammaglobulinemia, respiratory failure, pulmonary hypertension |
| url | http://journals.seedmedicalpublishers.com/index.php/cmi/article/view/1521 |
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